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April 2nd, 2007 at 2:12 pm

New “Selfish Gene” Produces Safe Mosquitoes

A class of selfish genes that cause the death of all offspring that do not inherit them could be used to help the spread of genetically modified mosquitoes that are resistant to malaria, scientists say.

The release of genetically modified mosquitoes that cannot pass malaria to people has been proposed as a new approach to controlling the disease, which kills up to 2.7 million people each year….

A class of selfish genes that cause the death of all offspring that do not inherit them could be used to help the spread of genetically modified mosquitoes that are resistant to malaria, scientists say.

The release of genetically modified mosquitoes that cannot pass malaria to people has been proposed as a new approach to controlling the disease, which kills up to 2.7 million people each year, but the strategy relies on the insects replacing their normal cousins in the wild.

Research in the US suggests that the chances could be improved by tying malaria resistance genes to another set of genes that kill offspring that do not inherit them.

These genes are known as “Medea elements” and they work generally through the female line, spreading rapidly through the population by ensuring that all living offspring carry them.

Via Times Online

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