Differences in estrogen and progestin drugs mean that women should not rule out hormone therapy after menopause despite highly publicized negative reports, a new study suggests.

Researchers from University of California, Davis, Duke University in Durham, North Carolina and Harvard University in Boston, Massachusetts say that not all estrogens and progestins are alike and that they behave differently in various tissues in the body.

Their findings contradict those of the well-known Women’s Health Initiative, which found that women on combination estrogen and progestin therapy had a slightly higher risk of heart attacks, strokes and blood clots than women taking a placebo. The study was shut down after this discovery.

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