A prize meant to inspire antiaging research has been awarded to a scientist who rejuvenated middle-aged mice, making them grow biologically younger while extending their lifespan.

The first-ever Methuselah Mouse Rejuvenation Prize was awarded to Stephen Spindler of the University of California, Riverside for research called “astounding” because it worked in mice later in life.

The intervention extended the average and maximum lifespan of the mice by 15% and reduced the number of deaths from cancer, the risk of which normally increases with age. DNA microarray analysis—a technique for examining the activity of genes—confirmed that the mice actually became physiologically younger.

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