In a special collection of articles published beginning 1 July 2005, Science Magazine and its online companion sites celebrate the journal’s 125th anniversary with a look forward — at the most compelling puzzles and questions facing scientists today. A special, free news feature in Science explores 125 big questions that face scientific inquiry over the next quarter-century; accompanying the feature are several online extras including a reader’s forum on the big questions.


Top 5 Questions:

  1. What Is the Universe Made Of?
  2. What Is the Biological Basis of Consciousness?
  3. Why Do Humans Have So Few Genes?
  4. To What Extent Are Genetic Variation and Personal Health Linked?
  5. Can the Laws of Physics Be Unified?

Whole list.