How Down Syndrome Protects Against Cancer

How Down Syndrome Protects Against Cancer

 Using customized stem cells, researchers showed that Down syndrome protects against cancer by preventing tumors from forming their own blood vessels. 

For decades scientists have known that people with Down syndrome, who have an extra copy of chromosome 21, get certain types of cancer at dramatically lower rates than normal. Now, partly by using stem cells derived from the skin of an individual with Down syndrome, researchers at Children’s Hospital Boston have pinpointed the gene that appears to underlie the cancer-protective effect.

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