Scientists are engineering Rhodococcus bacteria to boost production of lipids, which can be converted into biodiesel.
While most attempts to engineer biofuel-producing microbes have focused on well-known organisms such as yeasts and E. coli, scientists also hope to co-opt the unique metabolic functions of some of the microbial world’s less-studied creatures. Anthony Sinskey and his team at MIT have been cataloguing the genomic secrets of Rhodococcus bacteria, soil-dwelling microbes known to eat a variety of toxic compounds. The goal is to make a biodiesel-producing organism that can use a variety of sources as fuel. “We have done a lot of the basic chemistry and biology,” says Sinskey. “Now we need to figure out how to maximize yields.”