Potential Treatment for Huntington’s Disease

091115134134-large

Normal synaptic activity in nerve cells protects the brain from the misfolded proteins associated with Huntington’s disease, researchers have discovered.

Investigators at Burnham Institute for Medical Research (Burnham), the University of British Columbia’s Centre for Molecular Medicine and Therapeutics and the University of California, San Diego have found that normal synaptic activity in nerve cells (the electrical activity in the brain that allows nerve cells to communicate with one another) protects the brain from the misfolded proteins associated with Huntington’s disease. In contrast, excessive extrasynaptic activity (aberrant electrical activity in the brain, usually not associated with communication between nerve cells) enhances the misfolded proteins’ deadly effects.

Continue reading… “Potential Treatment for Huntington’s Disease”

0