Talking to the Defect

By Futurist Thomas Frey

The Seductive Logic of Having a Conversation with Abstract Concepts

Can you talk to conspiracy theories? To economic recessions? To your own lack of motivation? What about contrails, unsolved crimes, the magnetosphere, or your personal biases?

The short answer: yes, if you’re willing to accept that you’re not actually talking to these things—you’re talking to AI models sophisticated enough to simulate their behavior, explain their mechanisms, and respond as if they were entities with agency.

The longer answer is more unsettling: we’re going to do this whether it’s philosophically coherent or not, because conversational interfaces are irresistibly compelling. And the results will range from genuinely helpful to dangerously misleading depending on what we’re trying to give voice to and why.

The concept of “talking to the defect”—using AI to transform complex systems into conversational partners—extends far beyond medicine. Any phenomenon that can be modeled can theoretically be given voice. But there’s a dangerous assumption embedded in this entire framework: that giving something a voice makes it more trustworthy, more comprehensible, more real.

Let me walk you through where conversational systems become transformative, where they become actively dangerous, and why we’re building the oracles first and planning to figure out the difference later.

By Futurist Thomas Frey

The Question Nobody Thought to Ask

What if instead of analyzing your cancer, you could interview it? Not metaphorically—literally ask your tumor what it needs to survive, why it’s growing, what would kill it most effectively. What if your autoimmune disease could explain exactly why your immune system is attacking your body and what would make it stop?

This isn’t science fiction. It’s the logical endpoint of AI-powered diagnostic systems that can simulate complex biological processes and translate them into conversational interfaces. And it changes everything about how we diagnose, treat, and understand disease.

The concept comes from software engineering: “talking to the defect.” When code fails, instead of manually debugging thousands of lines, AI systems can simulate the defect’s behavior and explain—in plain language—what’s wrong, why it’s happening, and how to fix it. AI business developer Dave Blundin articulated this breakthrough in diagnostic methodology: give the problem a voice.

Now extend that concept to medicine. Your illness becomes your diagnostic partner. The defect in your body explains itself. The disease that’s killing you tells you how to kill it first.

Let me walk you through why this represents fundamental transformation in medical diagnosis, what becomes possible when diseases can explain themselves, and how quickly this shifts from theoretical to clinical reality.

Tag: Talking to the Defect

Talking to the Defect: When Your Disease Becomes Your Diagnostic Partner

The Question Nobody Thought to Ask