Hepnalysis is creating 3D bio-printed human liver models to detect the toxicity of drugs and reduce costs in the development of medicines.
To create liver human models bio-printed in 3D to detect the toxicity of drugs and reduce costs in the development of medicines is the objective of the Hepnalysis project, promoted by Cytes Biotechnologies, a spin-off by the UB with its base in the Barcelona Science Park (PCB), and the French company CTIBiotech.
The liver damage caused by medicines is a medical, scientific and public health-problem which is becoming more important every day. The hepatic injury induced by idiosyncratic drugs, known as drug-induced liver injury (DILI), is an usually under-diagnosed pathology that affects between one and two million patients per year worldwide. Also, it is the most common cause of acute liver failure –more than 50% of the cases– and the primary reason why the drugs are removed from the market –about 30%– and hospitalizations related to medicines.
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