How the Industrial Metaverse Is Revolutionizing Manufacturing

What once required a team of engineers physically pushing car chassis through factory assembly lines is now handled entirely in simulation. At BMW, digital twins—virtual replicas of entire factories—allow engineers to test and refine production processes long before a single piece of machinery is installed. This shift is part of a larger transformation happening in manufacturing, driven by what’s now being called the industrial metaverse.

While consumer visions of the metaverse have faltered, the industrial application of these technologies is thriving. The industrial metaverse—an ecosystem of interconnected simulations, sensors, 3D models, and augmented reality—offers manufacturers the ability to virtually plan, test, and optimize physical processes in a digital environment. According to the World Economic Forum, the industrial metaverse is expected to reach a global market value of $100 billion by 2030.

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Sharpening the Sky: How UT4 and Laser Technology Revolutionize Ground-Based Astronomy

Set against the star-filled skies of Chile’s Atacama Desert, UT4—one of four 8-meter telescopes at the European Southern Observatory’s Very Large Telescope (VLT) array in Paranal—stands as a technological marvel. With its advanced adaptive optics system, UT4 delivers images so sharp they rival those captured from space.

At night, beams of light erupt from UT4’s dome, slicing through the darkness. These beams originate from the 4 Laser Guide Star Facility (4LGSF), which allows the telescope to create artificial stars high above the Earth. The lasers excite sodium atoms located about 90 kilometers up in the atmosphere, causing them to glow. These glowing spots act as reference points, or “guide stars,” allowing astronomers to measure how Earth’s atmosphere distorts incoming light.

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LEAP 71 Advances Rocket Propulsion with AI-Driven Engine Design

LEAP 71, a company focused on computer-aided engineering, is expanding its computational development platform to design rocket engines capable of generating thrust in the meganewton range. Building on successful trials of smaller engines, the company is now developing two new reference propulsion systems: the 200 kN XRA-2E5 aerospike engine and the 2000 kN XRB-2E6 bell-nozzle engine.

At the core of this initiative is “Noyron,” a generative development model that encodes engineering logic into software. This model automates the creation of manufacturable rocket engine designs, including complex turbomachinery components necessary for engine functionality.

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Advancing MSC-Based Therapies: Overcoming Manufacturing Barriers with the Cymerus Platform

Mesenchymal stem/stromal cells (MSCs) are emerging as a promising tool in cell therapy due to their strong immunomodulatory and anti-inflammatory properties, their capacity for tissue regeneration, and a favorable safety profile. Unlike other cell-based therapies, such as CAR T cells that may trigger severe immune responses like cytokine storms, wild-type MSCs have shown no such adverse reactions when administered to humans. However, the widespread clinical application of MSCs has been limited by challenges in producing therapeutically effective cells consistently and at scale. To date, only one MSC-based therapy has been approved by the U.S. Food and Drug Administration (FDA).

A key obstacle in developing MSC therapies is the ongoing requirement for new tissue donations from various donors. This dependence leads to high variability and restricted batch sizes due to the limited expansion capacity of each donor-derived sample.

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Moon Mining for the Future: How Helium-3 Could Power Clean Energy and Quantum Computing

A new frontier in space resource utilization is emerging as Interlune, a Seattle-based startup, sets its sights on mining helium-3 from the Moon. This rare gas, nearly absent on Earth but relatively abundant on the lunar surface, holds immense potential for clean energy production and the advancement of quantum computing.

Interlune, founded by former Blue Origin president Rob Meyerson, has become the first private company to extract and sell helium-3 sourced from the Moon. With plans to begin supplying the gas to customers by 2029, the company is positioning itself at the cutting edge of lunar mining. Each kilogram of helium-3 is valued at around $20 million and contains approximately 7,400 liters of gas at standard temperature and pressure.

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USC Research Demonstrates Quantum Advantage in Solving Complex Optimization Problems

A newly published study from the University of Southern California (USC) has provided strong evidence that quantum computers can outperform classical supercomputers in solving complex optimization problems, marking a significant milestone in the field of quantum computing known as quantum advantage.

The research, published in Physical Review Letters, focuses on quantum annealing, a specialized form of quantum computation that identifies low-energy states in a system—these states correspond to optimal or near-optimal solutions. While previous efforts have aimed to demonstrate quantum advantage in exact optimization, this study shifts focus to approximate optimization, where finding a solution close to the best possible one is often sufficient for practical purposes.

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MIT Engineers Create Stretchable Yet Strong Metamaterials Using “Double-Network” Design

In the field of metamaterials—engineered materials with tailored microstructures—the dominant pursuit has long been “stronger is better.” These synthetic materials often mimic lattice structures to maximize stiffness and strength, but this traditionally comes at the expense of flexibility. Now, MIT engineers have broken new ground by developing a metamaterial that is both strong and stretchable, challenging a long-standing trade-off in materials science.

The innovation, detailed in Nature Materials, centers on a “double-network” design inspired by hydrogels. Hydrogels achieve their stretchiness and toughness by combining two polymer networks—one stiff, the other soft. Adapting this idea to metamaterials, the MIT team engineered a structure consisting of rigid struts interwoven with softer, spring-like coils, both printed from a plexiglass-like polymer using ultra-precise two-photon lithography.

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Antimicrobial Paint Offers Breakthrough in Fight Against Hospital Infections

Hospital surfaces are known hotspots for dangerous bacteria, contributing to the spread of healthcare-associated infections. But a new innovation from scientists at the University of Nottingham and University of Birmingham could help stop infections before they start: a germ-killing paint.

Researchers developed an antimicrobial coating by blending chlorhexidine digluconate (CHX)—a widely used antiseptic found in mouthwashes and skin cleansers—into commercially available epoxy resin. This simple yet effective formula turns everyday surfaces into powerful barriers against harmful microbes like MRSA, E. coli, Candida, and more.

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Beyond Human Touch: New Electronic Skin Features Unmatchable Fingerprint-Like Patterns

The chances of two people sharing identical fingerprints are incredibly slim—about 1 in 640 billion. Even identical twins, who share the same DNA, have unique fingerprint patterns. Now, scientists have taken this uniqueness a step further with the development of a revolutionary electronic skin that features artificial fingerprints with a probability of duplication 10²³² times lower than human fingerprints.

A research team led by Professor Kyoseung Sim from the Department of Chemistry at UNIST (Ulsan National Institute of Science and Technology) has unveiled this cutting-edge electronic skin technology in a recent Nature Communicationspublication. The breakthrough could lay the groundwork for future AI-powered robots to possess uniquely identifiable fingertips—offering capabilities previously exclusive to biological organisms.

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POSTECH Scientists Develop Temperature-Insensitive High-Entropy Alloy for Extreme Environments

Researchers at Pohang University of Science and Technology (POSTECH) have developed a high-entropy alloy (HEA) that maintains both strength and flexibility across an exceptionally wide temperature range—from -196 °C to 600 °C. This breakthrough opens new possibilities for use in aerospace, automotive, and energy industries where materials are exposed to extreme or fluctuating temperatures.

The research team, led by Professor Hyoung Seop Kim from the Department of Materials Science and Engineering, the Graduate Institute of Ferrous Technology, and the Department of Mechanical Engineering at POSTECH, published their findings in the international journal Materials Research Letters.

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Scientists Develop Pneumatic Propeller System to Replace Diesel Engines on Ferries

A team of researchers has developed a pioneering methodology to replace diesel engines on ferry boats with pneumatic propellers, offering a cleaner, quieter, and potentially more cost-effective alternative for maritime transport.

The study, published in Energy Conversion and Management, outlines a system in which two air motors, each generating 250 kW, successfully powered a ferry along a fixed route in Finland’s maritime transport system. The experimental system demonstrated that pneumatic propulsion could meet the same performance standards as traditional diesel engines, but with significantly reduced environmental impact.

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Breakthrough Method Supercharges Large Cancer Drugs by Hijacking Natural Cell Entry Pathway

A new scientific breakthrough could dramatically improve cancer treatments by helping bulky, hard-to-deliver drugs enter cells more efficiently.

Researchers from Duke University, the University of Texas Health Science Center at San Antonio, and the University of Arkansas have discovered a way to significantly boost the cellular uptake of a promising class of cancer therapies known as PROTACs. These drugs work by degrading harmful proteins in cells but are often too large to penetrate cell membranes on their own.

The team found that a naturally occurring cell surface protein, CD36, can act as a transporter, helping PROTACs cross the cellular barrier. By modifying the drugs to exploit this transport mechanism, the researchers achieved up to 22.3 times higher drug uptake, resulting in up to 23 times more powerful tumor suppression—all without sacrificing drug stability or solubility. Their findings, published April 17 in Cell, could breathe new life into many large-molecule drugs previously deemed too unwieldy for therapeutic use.

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