For decades, certain diseases have loomed like unsolvable riddles—cancers that resist every treatment, brain disorders that defy pharmaceutical logic. The reason? Many of the proteins behind them simply can’t be drugged. They’re too chaotic, too slippery, too structurally unstable for anything to stick.
Until now.
Scientists at the University of Washington have just pulled off what many in the biotech world thought impossible: using AI to design protein binders that can target these so-called “undruggable” proteins—shapeshifting molecules at the heart of some of the deadliest diseases we know. Alzheimer’s. Advanced cancers. Chronic pain conditions. All suddenly within reach.
Continue reading… “AI Just Cracked the Code on the “Undruggable”—And Nothing in the Human Body Is Off-Limits Anymore”