AI Nerve-Stimulation Device Allowed Paralysed Patients To Walk And Cycle

By Bharat Sharma

A nerve-stimulation device controlled by a touchscreen tablet was recently able to help three completely paralysed patients walk, cycle, and even swim!In a research outlined on Monday, scientists gave a new leash of life of three people who had suffered serious spinal cord injuries that left them paralysed in a region called the “thoracic spine” situated below the neck and above the backMost patients with the nerve-stimulation implant suffered injuries one to nine years before receiving the treatment

A nerve-stimulation device controlled by a touchscreen tablet was recently able to help three completely paralysed patients walk, cycle, and even swim!

In a research outlined on Monday, scientists gave a new leash of life of three people who had suffered serious spinal cord injuries that left them paralysed in a region called the “thoracic spine” situated below the neck and above the back.

Continue reading… “AI Nerve-Stimulation Device Allowed Paralysed Patients To Walk And Cycle”
0

THIS LITTLE PILL CAMERA COULD BE THE END OF COLONOSCOPIES

by Alex Baker

A tiny camera that fits inside a pill-sized capsule has revolutionised cancer screening in Scotland.

Over two thousand patients have now used the PillCam rather than the more traditional invasive method of having a colonoscopy.

The PillCam has reduced waiting times for bowel cancer screening and allowed faster diagnoses, an important factor in battling the disease.

The procedure itself is technically called a colon capsule endoscopy (CCE). The tiny camera is swallowed like a pill and then travels through the digestive system, recording 50,000 images along its journey.

Continue reading… “THIS LITTLE PILL CAMERA COULD BE THE END OF COLONOSCOPIES”
0

At Last: New Synthetic Tooth Enamel Is Harder and Stronger Than the Real Thing

Delivering what has been so challenging to produce, researchers present an engineered analog of tooth enamel – an ideal model for designing biomimetic materials – designed to closely mimic the composition and structure of biological teeth’s hard mineralized outer layer. It demonstrates exceptional mechanical properties, they say.

Natural tooth enamel – the thin outer layer of our teeth – is the hardest biological material in the human body. It is renowned for its high stiffness, hardness, viscoelasticity, strength, and toughness and exhibits exceptional damage resistance, despite being only several millimeters thick.

Continue reading… “At Last: New Synthetic Tooth Enamel Is Harder and Stronger Than the Real Thing”
0

Scientists regrow frogs’ amputated limbs in massive leap for regenerative medicine

By Ian Smith 

Scientists in the US have successfully regrown the lost legs of a group of frogs in a significant advance for regenerative medicine.

The research is an important step to one day helping people who have experienced the loss of a limb and opens the door to the potential use of a similar treatment on humans in the future.

The African clawed frog used in the research does not have the ability to naturally regenerate a limb and was treated with a five-drug cocktail over 24 hours. That brief treatment set in motion an 18-month period of regrowth that restored a functional leg.

“It’s exciting to see that the drugs we selected were helping to create an almost complete limb,” said Nirosha Murugan, research affiliate at the Allen Discovery Centre at Tufts and first author of the paper outlining the experiment.

“The fact that it required only a brief exposure to the drugs to set in motion a months-long regeneration process suggests that frogs and perhaps other animals may have dormant regenerative capabilities that can be triggered into action”.

Continue reading… “Scientists regrow frogs’ amputated limbs in massive leap for regenerative medicine”
0

SCIENTISTS BUILD NEW DEVICE THAT MAY HELP PEOPLE WHO ARE BLIND ‘SEE’ IN INFRARED

Infrared goggles can even help wearers navigate in darkness, say researchers 

By Vishwam Sankaran

A new device that can help blind people navigate and avoid obstacles was developed by scientists using infrared goggles and an array of vibrating pads on the forearm. 

Unlike canes and many other tools commonly available to visually impaired people for navigation, the new device enables the full use of their hands, according to a yet-to-be peer-reviewed study on the device that was posted in the preprint repository arXiv this month.

“The most common tool available to them is the cane. Although the cane allows good detection of objects in the user’s immediate vicinity, it lacks the ability to detect obstacles further away,” researchers Manuel Zahn and Armaghan Ahmad Khan from the Technical University of Munich in Germany wrote in the study.

The new device also does not interfere with the user’s sense of hearing – which is extensively used by the visually impaired – according to the scientists.

It uses a pair of infrared cameras inserted in 3D-printed prototype goggles to capture a stereoscopic image that a small computer uses to create a map of the surrounding area.

Continue reading… “SCIENTISTS BUILD NEW DEVICE THAT MAY HELP PEOPLE WHO ARE BLIND ‘SEE’ IN INFRARED”
0

Quantum Operation Non-Invasive Glucose Monitor: World’s First-Ever Non-Invasive Needle-Less Wearable

By Nica Osorio 

Key Points

  • Quantum Operation Inc., announces a medical miracle at the CES 2022
  • The Japanese IoT startup claims it has developed a non-invasive glucose monitor
  • Called the Noninvassive Glucometer Wristband, the device promises to revolutionize diabetes management

Blood glucose monitoring is crucial in managing diabetes as it keeps track of the changes in a person’s blood sugar levels, which in effect, provides vital information on how food, exercise, stress and habits affect the disease.

Over the years, scientists, engineers and even tech giants have tried to come up with a non-invasive blood glucose monitoring device that diabetics can use, but to no avail. Interestingly, Quantum Operation, a Japanese healthcare IoT startup, claims that it has developed a Noninvasive Glucometer Wristband — a needle-less and accurate blood glucose monitoring wearable that is capable of non-stop monitoring.

Advanced medical technology

Quantum Operation’s Noninvasive Glucometer Wristband offers a far simpler and easier solution that will not require patients to prick their finger for a blood sample that would then be used on test strips of traditional glucose meters. But how is this even possible?

Continue reading… “Quantum Operation Non-Invasive Glucose Monitor: World’s First-Ever Non-Invasive Needle-Less Wearable”
0

A HUMAN SKIN ‘BAND-AID’ PRINTER IS LAUNCHING INTO SPACE

By Matthew Hart

In December of 2021 SpaceX sent its 24th cargo resupply mission to the International Space Station (ISS). On board the mission were various experiments—including ones involving plants and potential cures for cancer. A bioprinter that uses “viable cells” to print tissue structures was also aboard. And it makes human skin “band-aids.”

Design Taxi reported on the delivery of the bioprinter, or Bioprint FirstAid, which is a handheld device. The device, in the images above and below, uses a patient’s own skin cells to create tissue-forming patches to cover wounds. And, simultaneously, accelerate the healing process.

NASA notes the device—which kind of looks like a tape dispenser with a bendy syringe instead of tape—uses prepared bio-inks consisting of a patient’s own cells. The collection of human skin cells, coupled with a “crosslinking” material, form a “band-aid patch” in the case of an injury. (Unfortunately, it’s unclear what the cell band-aid looks like as it heals. Or after it has healed. Although it seems to spread as a clear, viscous liquid.)

Continue reading… “A HUMAN SKIN ‘BAND-AID’ PRINTER IS LAUNCHING INTO SPACE”
0

SMART BANDAGE CHECKS CHRONIC WOUNDS IN REAL-TIME

The VeCare platform comprises a chip, wound sensor, bandage (above), and app for real-time, point-of-care chronic wound monitoring.

BY NATIONAL UNIVERSITY OF SINGAPORE

A new smart wearable sensor can conduct real-time, point-of-care assessment of chronic wounds wirelessly via an app, according to a new study.

The sensor detects temperature, pH, bacteria type, and inflammatory factors specific to chronic wounds within 15 minutes, allowing for fast and accurate wound assessment.

Given the rapidly aging population, healthcare providers are seeing more patients suffering from non-healing wounds such as diabetic foot and chronic venous leg ulcers. Estimates suggest that about 2% of the world’s population suffer from chronic wounds.

Infection and repeated trauma often interrupt the healing processes for these chronic wounds, leading to severe stress, pain, and discomfort to afflicted patients.

For patients with diabetic foot ulcers, this can lead to more severe outcomes such as foot amputation. Timely care and proper treatment of chronic wounds are needed to speed up wound recovery. However, this requires multiple clinical visits for lengthy wound assessment and treatment, which adds to the healthcare cost.

The new sensor, described in the journal Science Advances, can help mitigate these consequences and relieve patients with chronic wounds from unnecessary distress.

Continue reading… “SMART BANDAGE CHECKS CHRONIC WOUNDS IN REAL-TIME”
0

Engineering Artificial Lungs With Help From Lizards

The lizard lung forms quickly by a leveraging simple mechanical process the researchers likened to a mesh stress ball, the common toy. As fluid fills the developing lung, the inner membrane pushes out against smooth muscle tissue. The muscle separates into a honeycomb-shaped mesh and the membrane bulges out through the gaps, creating the surface area needed for gas exchange. Credit: Image courtesy Celeste Nelson and Michael PalmerRead time:  5 minutesGet PDF Version

When it comes to studying lungs, humans take up all the air, but it turns out scientists have a lot to learn from lizards.

A new study from Princeton University shows how the brown anole lizard solves one of nature’s most complex problems — breathing — with ultimate simplicity. Whereas human lungs develop over months and years into baroque tree-like structures, the anole lung develops in just a few days into crude lobes covered with bulbous protuberances. These gourd-like structures, while far less refined, allow the lizard to exchange oxygen for waste gases just as human lungs do. And because they grow quickly by leveraging simple mechanical processes, anole lungs provide new inspiration for engineers designing advanced biotechnologies.

Continue reading… “Engineering Artificial Lungs With Help From Lizards”
0

Lab-Grown Embryo Research Is Poised to Transform Medicine

New advances in stem cell science could alleviate devastating early-life conditions. But this comes with a moral conundrum.  

ACCORDING TO MULTIPLE studies, one in three pregnancies results in miscarriage, and one in 33 babies that are born will have a birth defect, due to the embryo forming incorrectly in the womb. Studying how the embryo develops can help us find ways to bring these numbers down. In 2022, we will see advances in this research thanks to stem-cell-based, embryo-like structures that can be grown in the lab.

Stem cells offer a powerful way to study the early development of the embryo. They can be grown in the lab in vast numbers and can be pushed toward making a huge assortment of cell types, including brain, blood, bone, and muscle.

Recently, several researchers have found ways to join stem cells together into small 3D balls of cells, which facilitate the creation of tiny embryo-like structures. These are currently rudimentary—the structures can be variable, they are inefficient to create and are unable to develop much further. Next year, we are likely to see improvements, with more advanced embryo-like structures made from stem cells. And we are also likely to see scientists using these models to investigate specific problems, such as how the embryo implants into the uterus, how organs start to develop or how the embryo ensures that cells are in the right positions.

Continue reading… “Lab-Grown Embryo Research Is Poised to Transform Medicine”
0

Innovative silicon nanochip can reprogram biological tissue in living body

A silicon device that can change skin tissue into blood vessels and nerve cells has advanced from prototype to standardized fabrication, meaning it can now be made in a consistent, reproducible way. As reported in Nature Protocols, this work, developed by researchers at the Indiana University School of Medicine, takes the device one step closer to potential use as a treatment for people with a variety of health concerns.

The technology, called tissue nanotransfection, is a non-invasive nanochip device that can reprogram tissue function by applying a harmless electric spark to deliver specific genes in a fraction of a second. In laboratory studies, the device successfully converted skin tissue into blood vessels to repair a badly injured leg. The technology is currently being used to reprogram tissue for different kinds of therapies, such as repairing brain damage caused by stroke or preventing and reversing nerve damage caused by diabetes.

Continue reading… “Innovative silicon nanochip can reprogram biological tissue in living body”
0

Yale researchers develop mRNA-based lyme disease vaccine

Yale researchers have developed an mRNA vaccine that targets the antigens found in tick saliva in order to alert individuals to tick bites as well as prevent the tick from feeding correctly, thereby reducing its ability to transmit pathogens. 

By Cate Roser

Yale researchers have developed an mRNA vaccine against lyme disease that triggers an immune response at the site of a tick bite and provides partial protection against the disease-causing bacteria. 

In a paper published on Nov. 17 in the Science Translational Medicine journal, scientists studied specific ticks called “Ixodes scapulari” that carry a lyme-disease-causing bacteria called “Borrelia burgdorferi.”According to Gunjan Arora, one of the co-first authors of the paper and an associate research scientist at the Yale School of Medicine, lyme disease is the fastest-growing vector-borne illness in the United States, with close to half a million people affected every year. Currently, there are no commercially available vaccines for lyme disease. This novel vaccine is unique in that it targets the vector of transmission, the tick, rather than the actual pathogen itself. “Lyme disease is the most common Tick–borne human illness in the United States, leaving an urgent need for either therapies or preventative strategies, such as a vaccine,” Jacqueline Mathias dos Santos, a co-first author on the paper and a postdoctoral associate at the School of Medicine, wrote in an email to the News. “Our vaccine is unique in that we don’t actually target the pathogen, we target the vector … instead. This strategy can work for Borrelia because it takes around 24 hours of tick feeding for the pathogen to be transmitted. This offers a unique opportunity to disrupt transmission. Additionally, by targeting the vector, we don’t expect this to drive resistance by the pathogen.”

Continue reading… “Yale researchers develop mRNA-based lyme disease vaccine”
0