Scientists at the University of Wisconsin–Madison claim a significant breakthrough with the creation of the first 3D-printed brain organoids that exhibit functions akin to natural brain tissue. Senior author Su-Chun Zhang explains that these organoids, developed from stem cells, showcase communication between neurons, signal transmission, interactions through neurotransmitters, and the formation of networks with support cells within the printed tissue.
The challenge in creating brain organoids lies in the limited control over their final structure when stem cells self-assemble into three-dimensional tissues. This lack of control hinders researchers in designing the best brain organoids for their studies. While some have attempted 3D bioprinting, challenges include keeping soft, cell-filled “inks” in place and preventing the use of stiffer substances or scaffolding that hinder natural cell connections.
Continue reading… “Groundbreaking 3D-Printed Brain Organoids Mimic Natural Tissue Function”