Category: Medicine

If you have ever had your blood drawn, whether to check your cholesterol, kidney function, hormone levels, blood sugar, or as part of a general checkup, you might have wondered why there is not an easier, less painful way.

Now there might be. A team of researchers from Caltech’s Cherng Department of Medical Engineering has unveiled a new wearable sensor that can detect in human sweat even minute levels of many common nutrients and biological compounds that can serve as indicators of human health.

The sensor technology was developed in the lab of Wei Gao, assistant professor of medical engineering, Heritage Medical Research Institute investigator, and Ronald and JoAnne Willens Scholar. For years, Gao’s research has focused on wearable sensors with medical applications, and this latest work represents the most precise and sensitive iteration yet.

“We’ve done wearable sweat sensors before,” he says. “There were so many biomarkers we wanted to detect, but in the past we could not. There was no good way.”

Gao says previous versions of his sweat sensors relied on enzymes embedded within them to detect a limited number of relevant compounds. While antibodies could be used in sensors to detect more compounds at low concentrations, that technique had a big weakness: antibodies in the sensor can only be used once, meaning the sensors will wear out.

Continue reading… “New Wearable Sensor Detects Even More Compounds in Human Sweat”

An ultrasound sticker

Researchers have created a stamp-sized ultrasound sticker that can provide images of internal organs continuously for 48 hours.

Currently, ultrasounds require bulky and specialised equipment only available in hospitals and doctors’ offices.

But a new design by Massachusetts Institute of Technology (MIT) engineers might make the technology as wearable and accessible as buying plasters at the pharmacy.

The patch was tested in people doing activities such as jogging and drinking fluids.

Ultrasounds allow doctors to see live images of a patient’s internal organs, and wands and probes are used to direct sound waves into the body.

These waves reflect back out to produce high-resolution images of a patient’s heart, lungs and other deep organs.

MIT graduate student Chonghe Wang said: “Wearable ultrasound imaging tools would have huge potential in the future of clinical diagnosis.

Continue reading… “Researchers develop ultrasound stickers that can see inside the body”

Taken in pill form, the drug would eliminate cells in the human body that are responsible for advancing the ageing process – potentially doubling our lifespan. But is this desirable?

By Jessica Byrne

Are you ready to live an additional hundred years?

British computational biologist Dr Andrew Steele has published a new book on the longevity of human life, arguing it is entirely feasible for us to live well beyond a single century with the help of a certain kind of drug.

In the book, he states that research in the field of senolytics – drugs that work to eliminate cells that degrade tissue function – are already showing promising results and could become available on the market within the next decade.

‘I don’t think there is any kind of absolute cap on how long we can live,’ said Dr Steele. ‘I can’t see a physical or biological reason why people couldn’t live to 200 — the challenge is whether we can develop the biomedical science to make it possible.’

Once perfected, the drug would destroy ‘zombie cells’, scientifically known as senescent cells. These cells stop dividing over our lifespan, accumulate inside our bodies, and eventually release compounds that speed up processes of ageing.

In a 2020 trial, mice who were administered the drug showed improved physical function and extended health and lifespan. Given that gene functions in humans and mice are almost identical, many believe we could reap the same benefits.

Continue reading… “Drug that increases human lifespan to 200 years is in the works”

Liverpool Hospital is trialling smart gloves that are said to provide surgical trainees with instant and accurate feedback.

The surgical gloves, invented by engineers at Western Sydney University, have been built around low-cost sensors which can record hand movements in fine detail, giving trainee surgeons and their mentors actionable data to evaluate and improve on intricate surgical procedures.

The research team are working closely with surgeons and students at Liverpool Hospital to develop the technology, which will augment rather than replace traditional surgical training.

Dr Gough Lui, who led the work, believes the device could objectively measure the intricate hand manoeuvres of surgeons, allowing for clear and actionable feedback for trainees.

“Training surgeons in a more objective and evidence-based manner ensures evidence-based competency. Teachers will be able to give precise feedback on minute details post-surgery, and students can analyse their performance,” Dr Lui said.

Continue reading… “Liverpool Hospital trials smart gloves to train surgeons”

By Gabby Landsverk

• Semaglutide, a weight-loss drug, showed promise for treating obesity in recent research.
• Demand quickly exceeded supply after the FDA in June approved once-weekly semaglutide injections.
• However, some experts worry that we don’t yet understand the drug’s long-term effects.

2021 was a historic year for obesity treatment. In June, the Food and Drug Administration approved the weight-loss drug semaglutide, which some experts described as a “game-changer.”

The medication, initially developed to treat Type 2 diabetes, was the first drug treatment to be approved by the FDA for weight management since 2014. Wegovy, the brand of semaglutide sold by Novo Nordisk, is a once-weekly injection designed to balance out hunger hormones. It’s prescribed for people with a body mass index of 30 or more, or a BMI of 27 with related conditions such as diabetes.

Semaglutide was widely praised, prompting such high demand that there were shortages within months of Wegovy’s entrance into the market.

While questions remain about its long-term effects, the drug made a splash in healthcare this year, changing how experts and the public think about weight loss.

Continue reading… “A ‘game-changer’ weight-loss drug was approved in 2021. Demand was so high that there were shortages within months.”

By  National University of Singapore

A research team led by Professor Lim Chwee Teck from the National University of Singapore’s (NUS) Department of Biomedical Engineering and Institute for Health Innovation & Technology (iHealthtech), in collaboration with clinical partners from Singapore General Hospital, has developed a smart wearable sensor that can conduct real-time, point-of-care assessment of chronic wounds wirelessly via an app. A world’s first, the novel sensor technology can detect temperature, pH, bacteria type and inflammatory factors specific to chronic wounds within 15 minutes, hence enabling fast and accurate wound assessment.

With a rapidly aging population, healthcare providers are seeing more patients suffering from non-healing wounds such as diabetic foot and chronic venous leg ulcers. It has been estimated that about two percent of the world’s population suffer from chronic wounds. The healing processes for these chronic wounds are often interrupted due to reasons such as infection and repeated trauma, leading to severe stress, pain and discomfort to afflicted patients. For patients with diabetic foot ulcers, this can lead to more severe outcomes such as foot amputation. Timely care and proper treatment of chronic wounds are needed to speed up wound recovery. However, this requires multiple clinical visits for lengthy wound assessment and treatment, which adds to the healthcare cost. The NUS team’s innovation can help mitigate these consequences and relieve patients with chronic wounds from unnecessary distress.

The research was first published in the journal Science Advances on 21 May 2021.

Continue reading… “World’s first smart bandage detects multiple biomarkers for onsite chronic wound monitoring”