How hospitals are using AI to save their sickest patients and curb ‘alarm fatigue’

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Early tests suggest artificial intelligence can improve patient care in hospitals’ intensive care units while helping curb “alarm fatigue.”Woody Harrington / for NBC News

Early tests show artificial “assistants” can help doctors and nurses spot potentially deadly problems in time to take life-saving action.

From interpreting CT scans to diagnosing eye disease, artificial intelligence is taking on medical tasks once reserved for only highly trained medical specialists — and in many cases outperforming its human counterparts.

Now AI is starting to show up in intensive care units, where hospitals treat their sickest patients. Doctors who have used the new systems say AI may be better at responding to the vast trove of medical data collected from ICU patients — and may help save patients who are teetering between life and death.

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New research uncovers compelling link between gut bacteria, obesity and the immune system

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Researchers have discovered the immune system can directly alter populations of certain bacteria in the gut that affect how dietary fats are absorbed

An impressive new study from scientists at the University of Utah has described how an impaired immune system can alter the composition of the gut microbiome resulting in metabolic disease and obesity. Demonstrated in mouse experiments, the research suggests certain species of gut bacteria can prevent the gut from absorbing fat, pointing to exciting potential future anti-obesity therapies.

The research originated from an unexpected observation. Ongoing experiments in mice engineered to lack a gene called MyD88 surprisingly resulted in the animals gaining significant amounts of weight. The specific gene was being studied for its relationship to immune function in the gut. It was discovered that suppressing this gene resulted in lower production of immunoglobulin A (IgA) antibodies in the gut, but the real mystery was how this gut-related immune mechanism resulted in metabolic disease and obesity.

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Proteins trapped in glass could yield new medicinal advances

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The protein, captured in an extremely thin piece of glass — around 50 nanometres in diameter, is sliced up, atom by atom, with the help of an electrical field. It is then analysed through Atom Probe Tomography, and the 3D structure is recreated on a computer. Credit: Small: Volume 15, Issue 24, Atom Probe Tomography for 3D Structural and Chemical Analysis of Individual Proteins Gustav Sundell, Mats Hulander, Astrid Pihl, Martin Andersson Copyright Wiley-VCH Verlag GmbH & Co. KGaA. Reproduced with permission.

Researchers at Chalmers University of Technology, Sweden, have developed a unique method for studying proteins which could open new doors for medicinal research. Through capturing proteins in a nano-capsule made of glass, the researchers have been able to create a unique model of proteins in natural environments. The results are published in the scientific journal, Small.

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Antibiotics found in world’s rivers at levels up to 300 times above safe levels

 

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A new study has found that in over 100 of 700 river samples taken, antibiotic concentrations were at levels exceeding safe concentrations, with the Danube found to be the most contaminated river in Europe

In a massive global study, led by researchers at the University of York, hundreds of rivers around the world have been tested for levels of common antibiotics. The study found 65 percent of all samples contained some concentration of antibiotics, with the worst cases showing levels more than 300 times higher than the generally accepted safe threshold.

The study is the first to coordinate such a broad global survey of the world’s rivers, examining levels of 14 common antibiotics from 711 sites across 72 countries. John Wilkinson, one of the researchers coordinating this large project, suggests that alongside many regions never before monitored, this is the largest antibiotic survey ever conducted.

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Bioengineers 3D print complex vascular networks

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They’ll be essential to 3D-printed organs and replacement tissues.

Bioengineers are one step closer to 3D printing organs and tissues. A team led by Rice University and the University of Washington have developed a tool to 3D print complex and “exquisitely entangled” vascular networks. These mimic the body’s natural passageways for blood, air, lymph and other fluids, and they will be essential for artificial organs.

For decades, one of the challenges in replicating human tissues has been figuring out a way to get nutrients and oxygen into the tissue and how to remove waste. Our bodies use vascular networks to do this, but it’s been hard to recreate those in soft, artificial materials.

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Doctors who are kind have healthier patients who heal faster, according to new book

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 Which doctor would you pick: a physician who is kind and warm, or one who is cold but graduated at the top of the class in medical school?

A new book makes a strong argument for the ones who are kind and warm, not just because they’re more pleasant, but because they have better patient outcomes.

“Compassionomics: The Revolutionary Scientific Evidence That Caring Makes a Difference,” written by physician-scientist team Stephen Trzeciak and Anthony Mazzarelli, provides overwhelming evidence for the healing power of compassion.

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Maryland test confirms drones can safely deliver human organs

 

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Researchers from the University of Maryland attach a cooler containing a kidney to a DJI M600 Pro drone in preparation for a test flight.

When a patient who needs an organ transplantation is finally matched with a donor, every second matters. A longer wait between when an organ is removed from a donor and when it is placed into a recipient is associated with poorer organ function following transplantation. To maximize the chances of success, organs must be shipped from A to B as quickly and as safely as possible—and a recent test run suggests that drones are up to the task.

One transplant surgeon’s personal experience at the operating table, waiting for organs to arrive, prompted him to think of new forms of delivery. “I frequently encounter situations where there’s simply no way to get an organ to me fast enough to do a transplant, and then those life-saving organs do not get transplanted into my patient,” says Dr. Joseph Scalea of the University of Maryland Medical Center. “And that’s frustrating, so I wanted to develop a better system for doing that.”

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The future of pain management

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Access to painkilling medications that can’t cause addiction, abuse, and overdose would make life easier for prescribers and could save the lives of patients.

Development of such drugs has been slow-going, in part because scientists don’t completely know how chronic pain works. They believe the body has multiple pathways to chronic pain, and that means multiple targets for painkillers. But researchers don’t have proven ways to identify which pathway is causing the pain in each person.

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Self-Propelling pills could mean the end of needle vaccines

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These pills work like tiny speedboats.

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A new type of tiny motor can help shuttle life-saving vaccines to where they need to go. For infants or those of us who are squeamish around needles, that could mean a future with fewer shots and more effective medicine.

The problem with oral vaccines — ones that take pill form — is that they can sometimes get broken down by stomach acid or get spit right back up by a child. That’s why researchers are interested in tiny, molecular motors that can propel the pills through the body to their target, making orally-consumed medication more effective than ever before.

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We can now grow perfect human blood vessels in a lab

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The latest game changer in diabetes research might not be a new drug or a therapy. Instead, it could be a system of human blood vessels virtually identical to the ones currently transporting blood throughout your body.

What makes these blood vessels special is that they are the first ones grown in a lab — and they’ve already generated a new lead in diabetes treatment.

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Giving poop is the new giving blood

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A side effect of donating blood is the self-satisfaction in knowing that you’ve done your duty to help save a life. The whole process only takes about 15 minutes and you’re rewarded with a juice box and free cookies. While giving blood is super important—and always will be—if you really want to go the extra mile, you should consider donating your poop for use in fecal transplants, too.

According to a new report published in the journal Frontiers in Cellular and Infection Microbiology, “super-donors” are those whose microbiomes are swarming with good bacteria—ideal candidates to provide material for fecal transplants. With the help of these super poopers, doctors are working to eradicate irritable bowel syndrome, allergies, type 2 diabetes, asthma, Alzheimer’s disease, and certain cancers.

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Ping An Good Doctor launches commercial operation of One-minute Clinics in China

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Ping An Good Doctor’s first One-minute Clinic in Wuzhen, outside of Shanghai. Credit: Ping An Good Doctor.

The company announced last week then it had placed its One-minute Clinics across 8 provinces and cities in China and signed service contracts for nearly 1,000 units.

Last year, Ping An Good Doctor, a one-stop healthcare ecosystem platform from China, piloted unstaffed clinics that employ artificial intelligence called “One-minute Clinics” in the Wuzhen Scenic Area outside of Shanghai, which connect patients with a clinician on Ping An Good Doctor’s in-house medical team. Just last week, the company announced that it had placed its One-minute Clinics across 8 provinces and cities in China and signed service contracts for nearly 1,000 units, providing healthcare services to more than 3 million users.

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