People 50 and older have a lot to look forward to, according to Juvenescence’s Greg Bailey—mainly that we won’t be aging as fast or poorly as our parents. “Science fiction has become science,” said the UK-based anti-aging biotech’s CEO about the company’s completing its $100 million Series B round of financing last week. “I think the world is going to be shocked,” he said in an interview. In total, Juvenescence has now raised $165 million in just 18 months to fund longevity projects with the lofty goal of extending human lifespans to 150 years.
Patches could help repair damaged hearts.
Heart disease is the leading cause of death in the US for both men and women. According to the Centers for Disease Control and Prevention, 735,00 Americans have a heart attack each year, and 610,000 die of heart disease.
Those who survive heart attacks remain at serious risk for heart failure. During a heart attack, the network of blood vessels that delivers blood to the heart, called the coronary arteries, experiences a blockage due to buildup of cholesterol and fatty deposits. Blood can’t flow through to the heart, which means it doesn’t get the oxygen and nutrients it needs, causing tissue to die.
Heart attack survivors are thus left with a heart that’s weaker, making everyday tasks like lifting objects or climbing stairs exhausting or even dangerous. Restoring damaged heart tissue has proved difficult if not impossible, but a research team from Imperial College London has a new tool they hope will be able to heal wounded hearts.
Do you remember the strange thrill of losing a tooth when you were a child? On the one hand, you had the distressing feeling of seeing blood and feeling it pop out. At the same time, you knew something exciting was going to happen when you put it under your pillow. If you were lucky, by the next morning, the tooth was gone and some money had magically appeared.
Institute for Molecular Engineering researchers have developed a “lab-on-a-chip” that could help us understand how single stem cells react to different molecules and environments. (Credit: Zhang et al.)
A new “lab-on-a-chip” can examine thousands of individual live cells over a weeklong period, performing experiments that would take more than 1 million steps in a laboratory.
The credit-card-sized, microfluidic device not only saves time and money, but also offers a new glimpse into how single stem cells react to different molecules and environments.
When researchers examined neural stem cells on the device and analyzed the data, they found several new rules that determine the timing and signaling sequences necessary for the cells to differentiate or renew themselves. The finding could have implications in understanding brain development or in treating patients with immunotherapy.
Apparently, the newest scientific discovery can possibly leave dentures and implants in the past, and make millions of people extremely happy.
These two methods for a missing tooth or teeth can lead to serious dental health issues, such as discomfort and irritations, difficulties to eat, and pain in the case of dentures, while implants can cause infections, nerve damage, injury or damage to the surrounding structures, and sinus problems.
An automated system that uses robots has been designed to rapidly produce human mini-organs derived from stem cells. Researchers at the University of Washington School of Medicine in Seattle developed the new system.
The advance promises to greatly expand the use of mini-organs in basic research and drug discovery, according to Benjamin Freedman, assistant professor of medicine, Division of Nephrology, at the UW School of Medicine, who led the research effort.
Automated robots now have the tools to grow imitation, simplified human organs out of stem cells. Thankfully, we weren’t transported to a sci-fi dystopia where the machines have risen up and started to farm humans, but rather a world where pharmaceutical and other biomedical research just became much easier and faster.
Give these robots some pluripotent stem cells (stem cells that can become any type of cell), and 21 days later they’ll have finished a complicated experiment testing out the effects of a drug or genetic manipulation on some human-like, lab-grown kidneys. According to research published yesterday, May 17, in Cell: Stem Cell, the process is much faster and more reliable than when humans grow the same mini-organs.
iPS procedure raises hopes for alternative to donations and artificial organs
TOKYO — Japan is set to host the world’s first clinical trials involving the use of induced pluripotent stem (iPS) cells to treat heart failure.
A special health ministry panel on Wednesday gave Osaka University the green light to carry out the study, pending final authorization from the health minister. This would be the second instance of using iPS-derived cells for disease treatment in Japan, after groundbreaking trials involving retinal cells launched in 2014.
It’s the closest we’ve come to growing transplantable hearts in the lab
Of the 4,000 Americans waiting for heart transplants, only 2,500 will receive new hearts in the next year. Even for those lucky enough to get a transplant, the biggest risk is the their bodies will reject the new heart and launch a massive immune reaction against the foreign cells. To combat the problems of organ shortage and decrease the chance that a patient’s body will reject it, researchers have been working to create synthetic organs from patients’ own cells. Now a team of scientists from Massachusetts General Hospital and Harvard Medical School has gotten one step closer, using adult skin cells to regenerate functional human heart tissue, according to a study published recently in the journal Circulation Research.
Wouldn’t it be great if your teeth could heal themselves without the need of a painful root canal?
Doctors at the Mayo Clinic have received FDA approval for a platform that can manufacture stem cells by the billions in just days, in contrast to previous methods of making stem cells that took months.
Americans spend between one and four billion dollars a year treating hair loss. Now, four surgeons in the U.S. are testing a stem cell treatment in a non-surgical procedure. Overseas trials in Japan and Egypt are already showing some success.