Self-assembling molecules suffocate cancer cells within hours

By Sophia Koch

By deploying a newly developed drug against a major energy source of cancer cells, scientists at the Max Planck Institute for Polymer Research have developed a new way to eliminate them in mere hours. The technology relies on self-assembling molecules that take a potent form in the cellular environment, and in doing so effectively starve cancer cells of the oxygen they need to grow.

The technology at the heart of this research targets one of the key metabolic functions of cells in all living things called ATP, or adenosine triphosphate. This molecule is the primary energy carrier in cells, capturing chemical energy from the breakdown of food molecules and distributing it to power other cellular processes.

Among those cellular processes is the proliferation of cancer cells, and because of this we have seen ATP implicated in previous anticancer successes. The authors of the new study sought to cut off the supply of ATP, which is produced as mitochondria absorb oxygen and turn it into molecules.

Continue reading… “Self-assembling molecules suffocate cancer cells within hours”

Ford is all set to make a grand entry into the Metaverse with virtual automobiles and NFTs

After Hyundai Motors, Ford intends to create downloadable media elements featuring its goods and services

By Shashank Bhardwaj


American automobile giant Ford Motor Company is all set to make a grand entry into the Metaverse and Web 3.0. On September 2, the vehicle brand filed for 19 trademarks related to the crypto space with the United States Patent and Trade Office (USPTO). According to USPTO licensed trademark attorney Mike Kondoudis, the company has filed trademark applications for all of its major brands ‘claiming plans for virtual cars, trucks, vans, and clothing.’ 

On September 7, Kondoudis took his official Twitter handle to say, “????????FORD is making a big move into the Metaverse! The company has filed 19 trademark applications for all of its major brands claiming plans for:

 ▶️ Virtual cars, trucks, vans, and clothing

 ▶️ Online stores for NFTs

The car manufacturer intends to create downloadable artwork, text, audio, and video featuring its cars, SUVs, trucks, and vans, according to the USPTO. NFTs will authenticate all of these. The 19 applications include the FORD, F-150 LIGHTNING, MUSTANG, LIGHTNING, MUSTANG MACH-E, BRONCO, TRANSIT, ESCAPE, etc. 

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European Union to use Blockchain & NFTs to Fight Forgery

The EUIPO plans to have a working system by the end of 2023 and will create a registry system for recording all of the IP holders, logistics operations and retailers.

By BYRITU LAVANIA

The European Union has announced that it is working on a Blockchain and NFT-based system to fight forgery of physical goods.

The proposed system will be designed by the European Union Intellectual Property Office (EUIPO), and will be an output of more than five years of hard work. As per an issued document, the EU has already selected a top-tier framework for this project, and the document also gives general details about how the system will work.

Intellectual property (IP) holders will develop twin NFTs as a proof that a group of produced goods are authentic. 

As per the outline, these IP holders must be previously included as ‘approved signatories’ to build the goods on the tracking blockchain.

After transporting products through different checkpoints and a successful supply chain tracking, the solution will let IP holders be sure that the products reaching stores are authentic.

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United Airlines Is Building A Fleet Of Electric Flying Taxis

They have the potential to revolutionize air travel in cities around the world, United says.

By Eric Kiefer

On Thursday, United Airlines announced that it is investing $15 million in Eve Air Mobility with a conditional purchase agreement for 200 four-seat electric aircraft, plus an option to buy 200 more.

NEWARK, NJ — United Airlines is on the “Eve” of a new paradigm when it comes to air travel, the company says. And according to United, its goal of creating a fleet of electric flying taxis continues to lift off.

On Thursday, the Chicago-headquartered airline – which maintains a hub in Newark, New Jersey – announced that it is investing $15 million in Eve Air Mobility with a conditional purchase agreement for 200 four-seat electric aircraft, plus an option to buy 200 more. The first deliveries of the cutting-edge vehicles may come as early as 2026.

Under the terms of the agreement, the companies intend to work on future projects, including studies on the development, use and application of Eve’s aircraft and the urban air mobility (UAM) ecosystem.

This week’s announcement marks another big investment from United in flying taxis – or electric vertical take-off and landing vehicles (eVTOLs) – which “have the potential to revolutionize the commuter experience in cities around the world,” the airline claims.

What makes the vehicles so unique? According to United, rather than relying on traditional combustion engines, eVTOL aircraft are designed to use electric motors, providing carbon-free flights and making them excellent fits to serve as “air taxis” in urban markets.

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TrinamiX partners to build biometric driver authentication capability into vehicle trim

By Chris Burt

BASF subsidiary trinamiX has formed a partnership with Spain-based Grupo Antolin to integrate face biometrics for driver authentication into the latter’s product portfolio.

Grupo Antolin is a global developer of technologies for car interiors, and will integrate trinamiX Face Authentication in vehicle trim to confirm the identity of the driver as they approach the vehicle.

TrinamiX Face Authentication provides strong, patent-protected biometrics with liveness detection based on skin analysis, as described in a reference design developed through a collaboration with Qualcomm.

The deal extends trinamiX’s biometric technology beyond smartphones, for which it is offered for in-display authentication solutions.

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Cars could soon ‘run on thin air’ thanks to hydrogen breakthrough

Could cars one day run on thin air?

By Rob Waugh

It sounds like science-fiction, but in the future, cars could run on air itself – specifically, on the water carried within humid air.

Researchers at the University of Melbourne have created a prototype dry-air electrolyser that harvests hydrogen from air instead of liquid water.

In the near future, hydrogen is expected to be commonly used as a ‘clean’ fuel which creates no carbon dioxide during combustion.

The device absorbs moisture, then turns it into hydrogen and oxygen – the hydrogen can then be used as fuel.

The prototype device created by the Melbourne team was able to work for 12 consecutive days, even in a dry environment of around 4% humidity.

The researchers write: “This so-called direct air electrolysis (DAE) module can work under a bone-dry environment with a relative humidity of 4%, overcoming water supply issues and producing green hydrogen sustainably with minimal impact to the environment. “

The scientists said that the technology could help to overcome one of the key challenges of using hydrogen as a fuel – the availability of freshwater.

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New AI Algorithm Could Lead to an Epilepsy Cure

Epilepsy is a neurological condition in which brain nerve cell activity is disturbed, resulting in seizures.

The AI algorithm detects brain abnormalities that cause epileptic seizures.

International researchers working under the direction of University College London have created an artificial intelligence (AI) algorithm that can identify subtle brain abnormalities that cause epileptic seizures.

In order to create the algorithm that reveals where abnormalities occur in instances with drug-resistant focal cortical dysplasia (FCD), a major cause of epilepsy, the Multicentre Epilepsy Lesion Detection project (MELD) analyzed more than 1,000 patient MRI images from 22 international epilepsy centers.

FCDs are brain regions that have developed abnormally and often cause drug-resistant epilepsy. Surgery is typically used to treat it, however, finding the lesions on an MRI is an ongoing problem for physicians since MRI scans for FCDs can appear normal.

The scientists utilized about 300,000 locations throughout the brain to develop the algorithm, which measured cortical features using MRI scans, such as how thick or folded the cortex/brain surface was. After that, based on patterns and characteristics, professional radiologists classified examples as either having FCD or having a healthy brain, which served as the algorithm’s training data.

According to the results, which were published in the journal Brain, the algorithm was successful in identifying the FCD in 67% of cases in the cohort (538 participants).

Continue reading… “New AI Algorithm Could Lead to an Epilepsy Cure”

Uber Eats to Use Autonomous Electric Vehicles for Deliveries

Uber Eats orders will soon be arriving in style.

By Meara Isenberg

The company’s partnership with driverless vehicle maker Nuro kicks off this fall with deliveries in Texas and California.

Ever ordered Uber Eats and thought, “If only I didn’t have to tip my driver.” If you live in the right city, you may soon find out what that’s like. 

Uber is teaming up with Nuro to use the latter company’s autonomous, electric vehicles for food deliveries in a multiyear partnership, the companies announced Thursday. Deliveries begin this fall in Mountain View, California, and Houston, Texas, and the plan is for the service to expand to the greater Bay Area, according to a release. 

Nuro’s autonomous delivery vehicles are built specifically to carry food and other goods, the release says. They don’t contain drivers or passengers, and they run on public roads. Nuro has previously announced partnerships with companies including FedEx and Domino’s.

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AI is getting better at generating porn. We might not be prepared for the consequences.

Tech ethicists and sex workers alike brace for impact

By Kyle WiggersAmanda Silberling

A red-headed woman stands on the moon, her face obscured. Her naked body looks like it belongs on a poster you’d find on a hormonal teenager’s bedroom wall — that is, until you reach her torso, where three arms spit out of her shoulders.

AI-powered systems like Stable Diffusion, which translate text prompts into pictures, have been used by brands and artists to create concept images, award-winning (albeit controversial) prints and full-blown marketing campaigns.

But some users, intent on exploring the systems’ murkier side, have been testing them for a different sort of use case: porn.

AI porn is about as unsettling and imperfect as you’d expect (that red-head on the moon was likely not generated by someone with an extra arm fetish). But as the tech continues to improve, it will evoke challenging questions for AI ethicists and sex workers alike.

Pornography created using the latest image-generating systems first arrived on the scene via the discussion boards 4chan and Reddit earlier this month, after a member of 4chan leaked the open source Stable Diffusion system ahead of its official release. Then, last week, what appears to be one of the first websites dedicated to high-fidelity AI porn generation launched.

Continue reading… “AI is getting better at generating porn. We might not be prepared for the consequences.”

Solinftec unveils new sprayer robot for farms

Solinftec, a global leader in agricultural digitalization, has unveiled a new sprayer robot for applications on farms and in agriculture.

BY MARK ALLINSON

The company says it is expanding its Solix Ag Robotics offerings. In addition to its Solix Scouting robot, the company has unveiled its Solix Sprayer robot designed to detect and spray weeds.

In partnership with the manufacturing, research, and development company, McKinney Corporation, who will produce and manufacture the Solix spray robot, this new cutting-edge technology is slated to become commercially available in 2023 to the entire agricultural market including farmers, cooperatives, and ag-retailers. 

Leonardo Carvalho, Solinftec’s director of operations, says: “Solinftec’s partnership with McKinney Corporation will positively impact our ability to market and deliver Solix Ag Robotics by consolidating Solix’s scalability and accelerating service to the North American markets.

“It also supports Solinftec’s goal of making this technology available globally.”

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Innovative approach brings cell-reprograming therapy for heart failure closer to reality

By Ana Maria Rodriguez

Not too long ago the idea of taking, for instance, a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

Cell reprogramming is a main interest of the lab of Dr. Todd Rosengart, chair, and professor of the Michael E. DeBakey Department of Surgery at Baylor College of Medicine, whose research focuses on finding innovative therapeutic approaches for heart failure.

“Heart failure remains the leading cause of death from heart disease,” said Rosengart, DeBakey-Bard Chair in Surgery and professor of molecular and cellular biology at Baylor. “Nearly 5 million Americans can be expected to develop advanced congestive heart failure, and heart transplant or mechanical circulatory support implantation currently are the only options for patients with end-stage heart disease. However, these options are limited. We need to improve how to treat this devastating condition.”

After a heart attack, the parts of the heart muscle that die do not regenerate into new heart tissue; instead, they are replaced by a scar that does not help the heart to beat. “The idea behind cell reprogramming is to coach the heart to heal itself by inducing the scar tissue, which is made mostly of fibroblasts, to change into functional heart muscle,” said Rosengart, professor of heart and vascular disease at the Texas Heart Institute.

Researchers have succeeded at reprogramming fibroblasts from small animals to become heart muscle, with dramatic improvements in heart function. The challenge has been to apply this technology to human cells — human fibroblasts are more resistant to reprogramming. In this study, published in the journal Scientific Reports, Rosengart and his colleagues explored a novel strategy to enhance the reprogramming efficiency of human fibroblasts.

Continue reading… “Innovative approach brings cell-reprograming therapy for heart failure closer to reality”
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