New Injectable Therapy Shows Promise in Preventing Heart Failure After Heart Attack

Researchers have developed an innovative injectable therapy that could transform how heart attacks are treated and potentially prevent patients from developing heart failure. Administered intravenously shortly after a heart attack, the treatment helps the heart heal by activating the body’s immune system to support tissue repair and protect heart muscle cells from further damage. Remarkably, the therapy remained effective even when administered up to five weeks after the heart attack in preclinical trials.

The study, published in the April 25 issue of Advanced Materials, was conducted by a team of bioengineers from the University of California San Diego and chemists from Northwestern University. Their approach directly addresses a major clinical challenge: how to intervene early to stop the progression from heart attack to heart failure. According to Karen Christman, one of the study’s senior authors and a professor at UC San Diego, preventing heart failure remains a critical unmet medical need. She emphasized that this therapy is designed to fill that gap by acting as soon as possible after a heart attack to protect and preserve heart function.

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MIT Engineers Create Stretchable Yet Strong Metamaterials Using “Double-Network” Design

In the field of metamaterials—engineered materials with tailored microstructures—the dominant pursuit has long been “stronger is better.” These synthetic materials often mimic lattice structures to maximize stiffness and strength, but this traditionally comes at the expense of flexibility. Now, MIT engineers have broken new ground by developing a metamaterial that is both strong and stretchable, challenging a long-standing trade-off in materials science.

The innovation, detailed in Nature Materials, centers on a “double-network” design inspired by hydrogels. Hydrogels achieve their stretchiness and toughness by combining two polymer networks—one stiff, the other soft. Adapting this idea to metamaterials, the MIT team engineered a structure consisting of rigid struts interwoven with softer, spring-like coils, both printed from a plexiglass-like polymer using ultra-precise two-photon lithography.

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Toward a Fully 3D-Printed 3D Printer: Breakthrough Prototype by Brian Minnick

A fully self-replicating 3D printer has long been seen as a theoretical goal, largely hindered by the reliance on non-printable components such as motors and electronic controls. Developer Brian Minnick has unveiled a working prototype that marks a major step forward: a 3D printer built with core mechanical and electrical components that are themselves 3D-printed.

At the heart of the design is a custom-built, three-pole DC motor, composed almost entirely of 3D-printed parts. Coils are fabricated using a syringe-based extrusion method that deposits solder paste, which is then sintered to form conductive traces. These printed wires exhibit an impressively low resistance of 0.001 Ω-mm, adequate for use in magnetic motors.

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Scientists Move Closer to Regrowing Teeth Using Lab-Grown Cells

What if a missing tooth could be regrown—not by nature, but in a lab using your own cells? Scientists at King’s College London are turning that idea into a promising reality.

In collaboration with Imperial College London, researchers have made a major breakthrough in growing living teeth in the lab. By successfully replicating the natural environment needed for early tooth development, they’ve taken a crucial step toward the possibility of lab-grown teeth replacing traditional dental treatments like fillings and implants.

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Antimicrobial Paint Offers Breakthrough in Fight Against Hospital Infections

Hospital surfaces are known hotspots for dangerous bacteria, contributing to the spread of healthcare-associated infections. But a new innovation from scientists at the University of Nottingham and University of Birmingham could help stop infections before they start: a germ-killing paint.

Researchers developed an antimicrobial coating by blending chlorhexidine digluconate (CHX)—a widely used antiseptic found in mouthwashes and skin cleansers—into commercially available epoxy resin. This simple yet effective formula turns everyday surfaces into powerful barriers against harmful microbes like MRSA, E. coli, Candida, and more.

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Overland AI Demonstrates Autonomous Breaching Capabilities with Upgraded SMET at Army Innovation Event

Overland AI has successfully demonstrated its autonomous ground vehicle integrated with uncrewed aerial system (UAS)-capable payloads during a joint breaching experimentation initiative alongside the Sandhills Project and the 20th Engineer Brigade of the XVIII Airborne Corps. The demonstration took place at Project Convergence Capstone 5 (PC-C5), the U.S. Army’s leading technology innovation event.

The Seattle-based company, founded in 2022, focuses on delivering autonomous solutions to power modern ground operations. With over a decade of advanced research in robotics and machine learning, Overland AI aims to put cutting-edge autonomy directly into the hands of tactical operators. Central to this vision is its OverWatch command-and-control (C2) interface, designed to give commanders precise control over autonomous ground systems in complex, mission-critical environments.

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Beyond Human Touch: New Electronic Skin Features Unmatchable Fingerprint-Like Patterns

The chances of two people sharing identical fingerprints are incredibly slim—about 1 in 640 billion. Even identical twins, who share the same DNA, have unique fingerprint patterns. Now, scientists have taken this uniqueness a step further with the development of a revolutionary electronic skin that features artificial fingerprints with a probability of duplication 10²³² times lower than human fingerprints.

A research team led by Professor Kyoseung Sim from the Department of Chemistry at UNIST (Ulsan National Institute of Science and Technology) has unveiled this cutting-edge electronic skin technology in a recent Nature Communicationspublication. The breakthrough could lay the groundwork for future AI-powered robots to possess uniquely identifiable fingertips—offering capabilities previously exclusive to biological organisms.

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A Breakthrough in Emotional Sensing: Wearable Patch Reveals Hidden Feelings

Saying one thing while feeling another is a normal part of being human—but consistently hiding emotions can lead to serious psychological consequences like anxiety or panic attacks. To help healthcare providers better detect these hidden emotions, researchers led by a team at Penn State have developed a soft, stretchable, rechargeable sticker that can detect genuine emotional states by measuring physiological signals such as skin temperature, heart rate, and more—even when someone is putting on a brave face.

This innovative wearable patch was recently detailed in a study published in Nano Letters. It’s capable of simultaneously and accurately monitoring multiple emotional indicators in real time.

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POSTECH Scientists Develop Temperature-Insensitive High-Entropy Alloy for Extreme Environments

Researchers at Pohang University of Science and Technology (POSTECH) have developed a high-entropy alloy (HEA) that maintains both strength and flexibility across an exceptionally wide temperature range—from -196 °C to 600 °C. This breakthrough opens new possibilities for use in aerospace, automotive, and energy industries where materials are exposed to extreme or fluctuating temperatures.

The research team, led by Professor Hyoung Seop Kim from the Department of Materials Science and Engineering, the Graduate Institute of Ferrous Technology, and the Department of Mechanical Engineering at POSTECH, published their findings in the international journal Materials Research Letters.

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Scientists Develop Pneumatic Propeller System to Replace Diesel Engines on Ferries

A team of researchers has developed a pioneering methodology to replace diesel engines on ferry boats with pneumatic propellers, offering a cleaner, quieter, and potentially more cost-effective alternative for maritime transport.

The study, published in Energy Conversion and Management, outlines a system in which two air motors, each generating 250 kW, successfully powered a ferry along a fixed route in Finland’s maritime transport system. The experimental system demonstrated that pneumatic propulsion could meet the same performance standards as traditional diesel engines, but with significantly reduced environmental impact.

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New Algorithm Enhances Identification of Tumor Mutations for Personalized Cancer Treatment

Researchers at the University of Cambridge and the NIHR Cambridge Biomedical Research Centre have developed a novel algorithm, PRRDetect, designed to more accurately identify critical mutations in tumors. This advancement could significantly improve cancer treatment outcomes, particularly in the field of immunotherapy, by revealing specific vulnerabilities within individual tumors.

The research highlights the overlooked importance of small insertions and deletions (InDels) in cancer development. As the study team noted, “Despite their deleterious effects, small insertions and deletions (InDels) have received far less attention than substitutions.”

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KAIST Researchers Develop Groundbreaking Therapy to Restore Vision Through Retinal Regeneration

A research team at the Korea Advanced Institute of Science and Technology (KAIST) has developed a pioneering therapy capable of restoring vision by regenerating damaged retinal nerves—marking a significant milestone in the treatment of degenerative eye diseases. This breakthrough offers renewed hope to more than 300 million people worldwide who are at risk of blindness due to various retinal conditions.

Led by Professor Jin Woo Kim from the Department of Biological Sciences, the KAIST team discovered a method to achieve both retinal regeneration and vision recovery in mammalian models. The therapy targets a protein called PROX1 (prospero homeobox 1), which normally inhibits retinal repair processes. By neutralizing this protein, the team enabled damaged retinas to regenerate and restore visual function—an achievement that, until now, had not been possible in mammals.

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