Using NVIDIA Clara, Google DeepVariant, and Oxford Nanopore Technologies sequencing, the Stanford University School of Medicine has been able to identify genetic diseases in as little as 7.5 hours. In just hours, a team of researchers from Stanford University was able to find a pathogenic variant and diagnose the rare seizure-causing genetic disorder.
This ultra-rapid sequencing research was published in New England Journal of Medicine. The proposed method set a new world record for fastest DNA sequencing technique.
The research team accelerated both base calling and variant calling using NVIDIA GPUs on Google Cloud. They also sped up variant calling by turning it into an application with Clara Parabricks, a computational genomics application framework.
The team was able to optimize every step in the pipeline, including speeding up sample preparation and using nanopore sequencing on Oxford Nanopore’s PromethION Flow Cell. This allowed them generate more than 100 gigabytes worth of data per hour!
Continue reading… “Latest Stanford Research Breaks World Record In DNA Sequencing Technique Using AI That Can Help Clinicians Rapidly Diagnose Critical Care Patients”

