A new breakthrough technique could revolutionize the treatment of glioblastoma, a deadly brain cancer with a survival rate of only 6.8 percent within the first five years of diagnosis. The new technique involves the use of sound waves to permeate the blood-brain barrier, a line of defense that prevents toxins and pathogens from entering the brain, and allows chemotherapy drugs to reach the neurological tissues where the cancer can grow.
The technique was tested in a phase 1 in-human clinical trial with 17 patients who underwent surgery to remove their tumors and had an ultrasound device implanted. The device, a novel skull-implantable grid of nine ultrasound emitters made by French biotech company Carthera, repeatedly uses sound waves to permeate the barrier and reach the brain tumor. The chemotherapy drugs paclitaxel and carboplatin, which are typically unable to cross the blood-brain barrier, were then able to reach the brain.
Continue reading… “Revolutionary Brain Cancer Therapy Promises a Ray of Hope for Desperate Patients”

