Tag: dna

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Genes, Genetics, People Making a Difference

The Genetic “Swiss Army Knife” That Could Rewrite Medicine Without Leaving Scars

Gene therapy has always carried a built-in paradox: the very act of “fixing” DNA risks creating permanent scars that could linger for generations. Now Yale researchers say they’ve cracked a safer way forward—genetic surgery without the scars.

Instead of hacking DNA, which is permanent and fraught with risk, they’ve turned their attention to RNA—the fragile middleman between DNA and proteins. RNA doesn’t last, and mistakes here don’t echo through generations. That makes it the perfect target for rewriting genetic messages without reshaping the human blueprint.

Continue reading… “The Genetic “Swiss Army Knife” That Could Rewrite Medicine Without Leaving Scars”
Genes, Genetics, Intelligence, People Making a Difference

Google’s AI Is Decoding the Genetic “Dark Matter” That Controls Us All

For years, scientists stared at the human genome and shrugged. We mapped it, sequenced it, even gave it a name—the Human Genome Project. But when it came to understanding what most of that DNA actually does, we were flying blind. Only about 2% of our genetic code directly tells cells which proteins to build. The rest—an eerie 98%—was long dismissed as “junk.”

Not anymore.

Google DeepMind just dropped a molecular bombshell: AlphaGenome, an AI that doesn’t just read your DNA—it predicts how the darkest corners of it control your body’s machinery. It’s not just looking at genes. It’s reading the switches, regulators, silencers, enhancers, and hidden messages that tell those genes when, where, and how to act.

Continue reading… “Google’s AI Is Decoding the Genetic “Dark Matter” That Controls Us All”
DNA, Genes, Genetics, People Making a Difference

The DNA Shield You Didn’t Know You Needed: How Scientists Are Now Fortifying Life’s Fragile Code

Tucked deep inside every cell is a time bomb we rarely talk about—mitochondrial DNA. Unlike its nuclear cousin, this tiny genetic engine doesn’t have much of a repair crew. When it breaks, it breaks hard. And that microscopic failure can cascade into inflammation, tissue damage, and a long list of chronic diseases.

But now, a team of researchers at UC Riverside has built something straight out of a cellular science thriller: a chemical shield that locks onto mitochondrial DNA before it unravels. It doesn’t just repair damage—it prevents the loss entirely.

Meet mTAP, a mitochondria-targeting molecular sentinel that doesn’t just react to cellular stress. It outsmarts it.

Continue reading… “The DNA Shield You Didn’t Know You Needed: How Scientists Are Now Fortifying Life’s Fragile Code”
Biotech, DNA, Medical Breakthrough, Science & Technology News

Harvard University uncovers DNA switch that controls genes for whole-body regeneration

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A piece of non-coding DNA may hold the key to how humans could regenerate body parts

Humans may one day have the ability to regrow limbs after scientists at Harvard University uncovered the DNA switch that controls genes for whole-body regeneration.

Some animals can achieve extraordinary feats of repair, such as salamanders which grow back legs, or geckos which can shed their tails to escape predators and then form new ones in just two months.

Planarian worms, jellyfish, and sea anemones go even further, actually regenerating their entire bodies after being cut in half.

Now scientists have discovered that that in worms, a section of non-coding or ‘junk’ DNA controls the activation of a ‘master control gene’ called early growth response (EGR) which acts like a power switch, turning regeneration on or off.

Continue reading… “Harvard University uncovers DNA switch that controls genes for whole-body regeneration”

Agriculture, Biotech, Farming, Food, Genes, Science & Technology News

Next generation of biotech food heading for grocery stores

WASHINGTON (AP) — The next generation of biotech food is headed for the grocery aisles, and first up may be salad dressings or granola bars made with soybean oil genetically tweaked to be good for your heart.

By early next year, the first foods from plants or animals that had their DNA “edited” are expected to begin selling. It’s a different technology than today’s controversial “genetically modified” foods, more like faster breeding that promises to boost nutrition, spur crop growth, and make farm animals hardier and fruits and vegetables last longer.

The U.S. National Academy of Sciences has declared gene editing one of the breakthroughs needed to improve food production so the world can feed billions more people amid a changing climate. Yet governments are wrestling with how to regulate this powerful new tool. And after years of confusion and rancor, will shoppers accept gene-edited foods or view them as GMOs in disguise?

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Biotech, Cancer, Medical Breakthrough, Medicine, Science & Technology News

Scientists just found a novel, cheap way to use CRISPR gene editing to fight cancer

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Immunotherapy Holds Big Promise for Beating Cancer

CRISPR is by all accounts a fascinating technology. Its headline feature is that it can literally be used to slice, dice, and otherwise manipulate the body’s genetic code—functions that could carry staggering implications for treating everything from inherited disorders to cancer to HIV/AIDS one day.

Now, new (though extremely early) research suggests that CRISPR could be used to vastly improve upon a new form of cancer-fighting methods that turn the body’s own immune T cells into specially targeted killers that attack cancerous tissue.

Continue reading… “Scientists just found a novel, cheap way to use CRISPR gene editing to fight cancer”

Analysis, Biotech, Genes, Medical Breakthrough

End of ageing and cancer? Scientists unveil structure of the ‘immortality’ enzyme telomerase

 

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Making a drug is like trying to pick a lock at the molecular level. There are two ways in which you can proceed. You can try thousands of different keys at random, hopefully finding one that fits. The pharmaceutical industry does this all the time – sometimes screening hundreds of thousands of compounds to see if they interact with a certain enzyme or protein. But unfortunately it’s not always efficient – there are more drug molecule shapes than seconds have passed since the beginning of the universe.

Alternatively, like a safe cracker, you can x-ray the lock you want to open and work out the probable shape of the key from the pictures you get. This is much more effective for discovering drugs, as you can use computer models to identify promising compounds before researchers go into the lab to find the best one. Now a study, published in Nature, presents detailed images of a crucial anti-ageing enzyme known as telomerase – raising hopes that we can soon slow ageing and cure cancer.

Continue reading… “End of ageing and cancer? Scientists unveil structure of the ‘immortality’ enzyme telomerase”

Biotech, cutting edge, Healthcare, Medical Breakthrough

New CRISPR method takes on Duchenne Muscular Dystrophy

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The advance of CRISPR gene editing technology, which uses an RNA strand to guide an enzyme called Cas9 to cut a specific portion of DNA, has raised concerns and sparked debate as people envision a not-so-distant future populated by bioengineered super-crops, genetically flawless pets, and customized babies. While the method could be used for these purposes, it’s also showing potential as a valuable medical tool, with a seemingly new condition added each week to the list of what CRISPR may one day cure.

Continue reading… “New CRISPR method takes on Duchenne Muscular Dystrophy”

Analysis, Culture, Genes, Genetics

The immigrant maps of America: Genome study of over 770,000 people reveals the ancestral origins of each part of the country

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Scientists from AncestryDNA analysed genome-wide genotype data from 774,516 Americans

This allowed researchers to identify the genetic ‘clusters’ within, or the genetic communities

The study reveals ancestral origins and migration patterns for specific groups across the country

Continue reading… “The immigrant maps of America: Genome study of over 770,000 people reveals the ancestral origins of each part of the country”

Biotech, Breakthrough Thinking, Futurist, Genetics, Science & Technology News

New Study Confirms That the Future of Data Storage Is in DNA

DNA contains information about a living organism. It codes everything in an living being. That’s why it makes sense for corporations like Microsoft to invest in research that studies how DNA can be used to store data. Unlike most of the existing data storage devices out there, DNA doesn’t degrade over time, plus it’s very compact. For example, just four grams of DNA can contain a year’s worth of information produced by all of humanity combined.
Continue reading… “New Study Confirms That the Future of Data Storage Is in DNA”

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