A single HeLa cell in metaphase (during mitosis), imaged by a lattice light sheet microscope.
A new imaging platform called a “lattice light sheet” developed by Nobel laureate Eric Betzig and colleagues at the Howard Hughes Medical Institute’s Janelia Research Campus is a significant leap forward for light microscopy. It captures high-resolution images rapidly and minimizes damage to cells, so it can image the three-dimensional activity of molecules, cells, and embryos in fine detail over longer periods than was previously possible, according to the HHMI scientists. (Videos)
Continue reading… “New microscope captures ultra-high-resolution movies of live 3D biomolecules”