Researchers from The Grainger College of Engineering at the University of Illinois Urbana-Champaign have developed a groundbreaking nanopore sensing platform capable of detecting single biomolecules. Their work, recently published in Proceedings of the National Academy of Sciences, offers promising advancements for solid-state, label-free DNA sequencing, with far-reaching implications for precision medicine.
Nanopore sensors operate by detecting changes in ionic current as individual molecules pass through nanoscale openings. These devices come in two primary forms: biological nanopores and solid-state nanopores. While biological nanopore sequencing has already reached commercial use, engineers at Illinois Grainger aimed to develop a solid-state alternative that is more compatible with scalable manufacturing.
Continue reading… “Breakthrough in 2D Nanopore Technology Sets Stage for Faster, Cheaper DNA Sequencing”
