Research represents a major step forward in achieving new therapies for a whole host of neurological and mental disorders. Credit: Cornelia LI
Millions of patients suffering from neurological and mental disorders such as depression, addiction, and chronic pain are treatment-resistant. In fact, about 30% of all major depression patients do not respond at all to any medication or psychotherapy. Simply put, many traditional forms of treatment for these disorders may have reached their limit. Where do we go from here?
Research to be published in Nature Biomedical Engineering led by Maryam Shanechi, the Andrew and Erna Viterbi Early Career Chair in electrical and computer engineering at the USC Viterbi School of Engineering, paves the way for a promising alternative: personalized deep brain stimulation. The work represents a major step forward in achieving new therapies for a whole host of neurological and mental disorders.
Until now, the challenge of personalized deep brain stimulation has been the human brain itself. Mental disorders can manifest differently in each patient’s brain. Similarly, whether and how each patient’s brain activity and their symptoms will respond to stimulation can be very different. This makes it difficult to know the effect of stimulation in a given patient or how to change the dose of stimulation—that is, its amplitude or frequency—over time to tailor it to a patient’s needs.
Continue reading… “New realm of personalized medicine with brain stimulation”