Chemical Discovered Which ‘Makes Bone Marrow Repair Skin’

skin graft 234

Skin grafts trigger repair by bone marrow cells.

The chemical which summons stem cells from bone marrow to the site of a wound has been discovered by scientists in the UK and Japan.

The study, published in Proceedings of the National Academy of Sciences, identified the distress signal – HMGB1.

The authors believe it can be used to put “a megaphone in the system” to improve the treatment of injuries such as burns and leg ulcers…

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Doctors Perform Windpipe Transplant With Stem Cells

Doctors Perform Windpipe Transplant With Stem Cells 

 A patient’s collapsed lung, at right, is seen prior to a windpipe transplant which used tissue grown from the patient’s own stem cells.

Doctors have given a woman a new windpipe with tissue grown from her own stem cells, eliminating the need for anti-rejection drugs. “This technique has great promise,” said Dr. Eric Genden, who did a similar transplant in 2005 at Mount Sinai Hospital in New York. That operation used both donor and recipient tissue. Only a handful of windpipe, or trachea, transplants have ever been done.

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A Source Of Stem Cells From Men

A Source Of Stem Cells From Men 

 Stem cells from adult human testes normally produce only sperm, but when cultured in the lab with special growth factors, they begin to resemble embryonic stem cells and can differentiate into many adult cell types.

Stem cells from human testes could be used for personalized medicine.  Adult stem cells that behave much like embryonic ones have been isolated from human testes, raising hopes for a new source of versatile stem cells without genetic manipulation or the destruction of embryos. If the new stem cells can be used therapeutically, a simple testicular biopsy could provide the starting material for personalized regenerative medicine.

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New Biomaterial Could Help In Knee Cartilage Repair

New Biomaterial Could Help In Knee Cartilage Repair 

 Abnormal Cartilage

A new biomaterial developed by Cartilix, a biotech startup based in Foster City, CA, could dramatically improve the success rate of knee-cartilage repair surgery, making the procedure more accessible to patients with bad knees. The new material, called ChonDux, consists of a polymer hydrogel that, when injected into the knee during surgery, guides the regeneration of cartilage by stimulating repair cells in the body.

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