The ‘game-changing’ technique to create babies from skin cells just stepped forward

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Scientists in Japan made progress recently in the quest to combat infertility, creating the precursor to a human egg cell in a dish from nothing but a woman’s blood cells. The research is an important step toward what scientists call a “game-changing” technology that has the potential to transform reproduction.

The primitive reproductive cell the scientists created is not a mature egg, and it cannot be fertilized to create an embryo. But researchers have already created eggs out of mouse tail cells and fertilized them to produce viable pups, so outside scientists said the research is on track to one day achieve human “in vitro gametogenesis” — a method of creating eggs and sperm in a dish.

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Machine-learning system tackles speech and object recognition, all at once

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MIT computer scientists have developed a system that learns to identify objects within an image, based on a spoken description of the image.

Model learns to pick out objects within an image, using spoken descriptions.

MIT computer scientists have developed a system that learns to identify objects within an image, based on a spoken description of the image. Given an image and an audio caption, the model will highlight in real-time the relevant regions of the image being described.

Unlike current speech-recognition technologies, the model doesn’t require manual transcriptions and annotations of the examples it’s trained on. Instead, it learns words directly from recorded speech clips and objects in raw images, and associates them with one another.

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This “Robotic Skin” can turn pretty much anything into a robot

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Inanimate objects coming to life — the stuff of nightmares? Not so when you can control the objects thanks to “robotic skin.” Then it’s just really, really cool.

You don’t have to take our word for it, either. Yale researchers have actually created this robotic skin, and they posted a video of it in action on Wednesday— the same day they published their research on the tech in the journal Science Robotics.

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Building a better brain-in-a-dish, faster and cheaper

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UC San Diego researchers develop new protocol for creating human cortical organoids, mini-brains derived directly from primary cells that can be used to better explore and understand the real thing.

Writing in the current online issue of the journal Stem Cells and Development , researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

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CRISPR gene editing creates cocaine-proof mice, aims to crack addiction puzzle

Gene editing has already given us malaria-resistant mosquitoes and heat-resistant cows. Now, researchers from the University of Chicago may have topped both of those feats with their latest creation: Cocaine-resistant mice. Using the CRISPR-based gene-editing platform to modify the DNA of skin cells, researchers Xiaoyang Wu and Ming Xu have been able not only to create mice that are less likely to seek out cocaine than their counterparts, but are also immune to cocaine overdoses that killed mice without the same CRISPR-edited cells.

The process builds on previous work involving a modified enzyme called butyrylcholinesterase (BCHE), which is capable of naturally breaking down cocaine very rapidly. Unfortunately, its short half-life makes it ineffective in a clinical scenario, since it disappears before it has any long-term impact on the body’s response to cocaine. BCHE cannot be administered orally, which makes it ill-suited for use as a potential treatment.

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AI-Human “hive mind ” diagnoses pneumonia

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First, it correctly predicted the top four finishers at the Kentucky Derby. Then, it was better at picking Academy Award winners than professional movie critics—three years in a row. The cherry on top was when it prophesied that the Chicago Cubs would end a 108-year dry spell by winning the 2016 World Series—four months before the Cubs were even in the playoffs. (They did.)

Now, this AI-powered predictive technology is turning its attention to an area where it could do some real good—diagnosing medical conditions.

In a study presented on Monday at the SIIM Conference on Machine Intelligence in Medical Imaging in San Francisco, Stanford University doctors showed that eight radiologists interacting through Unanimous AI’s “swarm intelligence” technology were better at diagnosing pneumonia from chest X-rays than individual doctors or a machine-learning program alone.

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How Uber is getting flying cars off the ground

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It wants to fly you around cities as in the Jetsons, but there are still roadblocks to overcome before UberAir can take flight.

It’s 6 p.m. in Tokyo and my flying car is late. Three years late.

Back to the Future promised me flying cars (and hoverboards) by 2015. Yet here I am in 2018, standing in one of the world’s most high-tech cities and I have to walk. I don’t even get to do it in self-lacing shoes.

I’m in Tokyo for Uber Elevate, Uber’s third conference outlining its plans to get flying cars off the silver screen and into our skies in as little as two years. It’s a lofty ambition, but Uber has partnered with some big names in aviation and picked up its share of NASA alumni to help it get there.

The goal? UberAir. A future transport network in which air travel is as easy and on-demand as Uber rides are now. As simple as “push a button, get a flight.”

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My career as an international blood smuggler

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For years, Kathleen McLaughlin smuggled American plasma every time she entered China, home to the world’s largest and deadliest blood debacle. She had no other choice.

I started my decade-long turn as an international blood smuggler in 2004 with a mundane task: packing. I gently stacked a dozen half-liter glass vials into two soft-sided picnic coolers. The bottles held the components of a syrupy mix, a powerful medicine made from the immune system particles collected from thousands of people. A nurse would infuse the syrup into my veins, a treatment to keep my immune system under control, to halt its potentially paralyzing attacks on my nerves.

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You can bring your weed to the LA airport now

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LAX is totally cool with passengers packing it in their carry-ons—but if it’s illegal where you land, that’s on you.

It looks like travelers in Los Angeles won’t have to cram their weed inside balled-up socks or stash it in their ibuprofen bottles next time they fly—because LAX is totally chill about bringing pot into the airport now, ABC 13 reports.

This week, Los Angeles International Airport posted a new marijuana policy on its website, announcing that LAX and the LAPD will now let people stroll onto their flights carrying cannabis, as long as it’s under the legal limit.

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Exclusive: Tim Berners-Lee tells us his radical new plan to upend the World Wide Web

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With an ambitious decentralized platform, the father of the web hopes it’s game on for corporate tech giants like Facebook and Google.

Last week, Tim Berners-Lee, inventor of the World Wide Web, asked me to come and see a project he has been working on almost as long as the web itself. It’s a crisp autumn day in Boston, where Berners-Lee works out of an office above a boxing gym. After politely offering me a cup of coffee, he leads us into a sparse conference room. At one end of a long table is a battered laptop covered with stickers. Here, on this computer, he is working on a plan to radically alter how all of us live and work on the web.

“The intent is world domination,” Berners-Lee says with a wry smile. The British-born scientist is known for his dry sense of humor. But in this case, he is not joking.

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This super-reflective coating keeps buildings cool so we don’t need as much AC

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Buildings are already being painted white to help keep them cool. As temperatures increase, this new addition to the paint could help lower our massive air conditioning energy use.

One of the ironies of climate change is that as heat waves become more common, people use more air conditioning–and those air conditioners help drive more climate change, and make things hotter. By the middle of the century, as more people around the world can afford air conditioners, the number of units could more than triple and end up using as much electricity as China uses today for its entire economy.

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Culturally sensitive robots are here to care for the elderly

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Humans are living longer, healthier lives. That’s great, but there’s a downside — the growing elderly population requires an entire industry of (expensive) caregivers, and we’ll likely need even more of them in the future.

Care robots might be able to do some of that work. Researchers suspect robots could help elderly people with everything from staying active to remembering their medications. Now researchers in Europe and Japan are working to make sure those robots don’t offend the people they’re supposed to take care of — they’re making what they say are the world’s first robots with a sense of cultural norms.

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