POSTECH Scientists Develop Temperature-Insensitive High-Entropy Alloy for Extreme Environments

Researchers at Pohang University of Science and Technology (POSTECH) have developed a high-entropy alloy (HEA) that maintains both strength and flexibility across an exceptionally wide temperature range—from -196 °C to 600 °C. This breakthrough opens new possibilities for use in aerospace, automotive, and energy industries where materials are exposed to extreme or fluctuating temperatures.

The research team, led by Professor Hyoung Seop Kim from the Department of Materials Science and Engineering, the Graduate Institute of Ferrous Technology, and the Department of Mechanical Engineering at POSTECH, published their findings in the international journal Materials Research Letters.

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Scientists Develop Pneumatic Propeller System to Replace Diesel Engines on Ferries

A team of researchers has developed a pioneering methodology to replace diesel engines on ferry boats with pneumatic propellers, offering a cleaner, quieter, and potentially more cost-effective alternative for maritime transport.

The study, published in Energy Conversion and Management, outlines a system in which two air motors, each generating 250 kW, successfully powered a ferry along a fixed route in Finland’s maritime transport system. The experimental system demonstrated that pneumatic propulsion could meet the same performance standards as traditional diesel engines, but with significantly reduced environmental impact.

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New Algorithm Enhances Identification of Tumor Mutations for Personalized Cancer Treatment

Researchers at the University of Cambridge and the NIHR Cambridge Biomedical Research Centre have developed a novel algorithm, PRRDetect, designed to more accurately identify critical mutations in tumors. This advancement could significantly improve cancer treatment outcomes, particularly in the field of immunotherapy, by revealing specific vulnerabilities within individual tumors.

The research highlights the overlooked importance of small insertions and deletions (InDels) in cancer development. As the study team noted, “Despite their deleterious effects, small insertions and deletions (InDels) have received far less attention than substitutions.”

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KAIST Researchers Develop Groundbreaking Therapy to Restore Vision Through Retinal Regeneration

A research team at the Korea Advanced Institute of Science and Technology (KAIST) has developed a pioneering therapy capable of restoring vision by regenerating damaged retinal nerves—marking a significant milestone in the treatment of degenerative eye diseases. This breakthrough offers renewed hope to more than 300 million people worldwide who are at risk of blindness due to various retinal conditions.

Led by Professor Jin Woo Kim from the Department of Biological Sciences, the KAIST team discovered a method to achieve both retinal regeneration and vision recovery in mammalian models. The therapy targets a protein called PROX1 (prospero homeobox 1), which normally inhibits retinal repair processes. By neutralizing this protein, the team enabled damaged retinas to regenerate and restore visual function—an achievement that, until now, had not been possible in mammals.

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Adaptable Robots Poised to Revolutionize E-Waste Recycling in Europe

A team of European researchers has developed adaptable, AI-driven robots that could transform the way electronic waste is recycled — offering major benefits for both the environment and the economy.

At Electrocycling GmbH, one of Europe’s largest e-waste recycling facilities located near Goslar, Germany, up to 80,000 metric tons of electronic waste are processed annually. Despite modern equipment, over half of the staff still manually dismantle discarded electronics. This often involves removing dangerous lithium batteries from increasingly compact and complex devices — a process that is repetitive, labor-intensive, and potentially hazardous.

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Unlocking Earth’s Secrets from Space: NASA Develops Quantum Sensor to Measure Gravity

NASA’s Jet Propulsion Laboratory (JPL) in Southern California, along with academic and industry partners, is advancing a groundbreaking quantum sensing technology designed to measure gravity from space for the first time. Supported by NASA’s Earth Science Technology Office (ESTO), this effort aims to pioneer a new era of Earth observation using quantum-based instruments to reveal hidden features beneath the planet’s surface, such as underground aquifers, mineral reserves, and oil deposits.

Unlike static physical properties, Earth’s gravitational field continuously changes in response to the dynamic movement of mass below the surface. Detecting these subtle gravitational variations requires extremely sensitive tools. This is where gravity gradiometers come in—specialized instruments that measure how gravitational force changes over small distances. These changes, while imperceptible in daily life, provide critical insights into subsurface structures and are valuable for fields ranging from environmental science to national security.

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Flexible Brainstem Implant Offers New Hope for Hearing Restoration Beyond Cochlear Implants

Researchers at EPFL (École Polytechnique Fédérale de Lausanne) have developed a soft auditory brainstem implant (ABI) that could significantly improve hearing restoration for individuals who are not candidates for cochlear implants. Unlike traditional rigid ABIs, this new flexible device is designed to conform to the natural contours of the brainstem, reducing side effects and improving sound perception.

Cochlear implants have helped many people regain hearing by transmitting sound signals from the inner ear to the brain. However, these implants require an intact cochlear nerve to function. For individuals with damaged or missing cochlear nerves, auditory brainstem implants offer an alternative by directly stimulating the brainstem. Existing ABIs, made of rigid materials, do not fit the curved surface of the brainstem well, often resulting in unintended stimulation of surrounding nerves. This can cause side effects such as dizziness, facial twitching, and discomfort, leading to the deactivation of several electrodes and limiting the implant’s effectiveness.

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Breakthrough Method Supercharges Large Cancer Drugs by Hijacking Natural Cell Entry Pathway

A new scientific breakthrough could dramatically improve cancer treatments by helping bulky, hard-to-deliver drugs enter cells more efficiently.

Researchers from Duke University, the University of Texas Health Science Center at San Antonio, and the University of Arkansas have discovered a way to significantly boost the cellular uptake of a promising class of cancer therapies known as PROTACs. These drugs work by degrading harmful proteins in cells but are often too large to penetrate cell membranes on their own.

The team found that a naturally occurring cell surface protein, CD36, can act as a transporter, helping PROTACs cross the cellular barrier. By modifying the drugs to exploit this transport mechanism, the researchers achieved up to 22.3 times higher drug uptake, resulting in up to 23 times more powerful tumor suppression—all without sacrificing drug stability or solubility. Their findings, published April 17 in Cell, could breathe new life into many large-molecule drugs previously deemed too unwieldy for therapeutic use.

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Finger-Inspired Sensor Breakthrough Enhances Robotic Touch and Material Recognition

The development of increasingly advanced sensors is driving progress in fields such as robotics, security systems, virtual reality (VR), and high-tech prosthetics. Among these, multimodal tactile sensors—which detect various types of touch-related data like pressure, texture, and material composition—stand out for their potential to replicate the human sense of touch.

Despite significant advances in tactile sensor technology, two major challenges persist: detecting both the direction and magnitude of applied forces, and accurately identifying the materials that objects or surfaces are made from. Many existing sensors struggle to overcome these limitations.

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Scientists Develop Vascularized Lab-Grown Chicken for More Realistic Cultured Meat

Researchers at the University of Tokyo have developed a new method for growing lab-cultured chicken meat that mimics natural blood vessel systems, offering a potential breakthrough in the production of realistic, ethical alternatives to conventional meat. The team successfully produced nugget-sized pieces of chicken muscle using a bioreactor equipped with artificial vessels that deliver nutrients and oxygen evenly throughout the tissue—one of the major challenges in lab-grown meat production.

The innovation centers on a device called a perfusable hollow fiber bioreactor, which uses tiny, tube-like structures to replicate the function of blood vessels. These artificial vessels not only keep the cells alive by providing a steady supply of oxygen and nutrients but also guide muscle cell growth through microscopic anchors that help align the tissue properly.

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GPT-4.5 Reportedly Passes Turing Test—But What Does That Really Mean?

Recent headlines have claimed that an AI chatbot has officially passed the Turing test, marking what some see as a major milestone in artificial intelligence. These reports are based on a preprint study conducted by researchers Cameron Jones and Benjamin Bergen at the University of California, San Diego. Their study found that OpenAI’s GPT-4.5 was judged to be human more than 70% of the time during a controlled experiment—suggesting it has reached a new level of conversational realism.

The experiment, which has not yet undergone peer review, tested four large language models (LLMs): ELIZA, GPT-4o, LLaMa-3.1-405B, and GPT-4.5. A total of 284 participants were involved, alternating between roles as interrogators and witnesses. Interrogators engaged in text-based conversations with two entities—one human, one AI—via a split-screen interface for five minutes. At the end of each session, participants were asked to determine which was human.

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Singapore Researchers Turn Raindrops Into Efficient Renewable Energy Source

Researchers at the National University of Singapore have developed a novel system that can convert falling raindrops into usable electricity, enough to power 12 LEDs for 20 seconds. The innovation relies on a process called plug flow, where falling droplets move uniformly through a narrow vertical tube, maximizing the charge generated by each drop.

Led by Associate Professor Siowling Soh, the team demonstrated how this flow pattern significantly enhances the generation of electricity from water movement. Unlike conventional hydroelectric systems that require large-scale infrastructure and abundant water sources, this setup uses a simple, compact design involving a metallic needle and a 12-inch (32 cm) tall, 2-millimeter-wide polymer tube.

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