Cancer comes in more shades than just pink: Studies

We have even more reason to understand breast cancer as multiple diseases.

Every year we go though a full month of pink, pink and more pink, all in the name of “breast cancer awareness.” What once was a health-related cause has become the feel-virtuous-and-buy-stuff season wedged between back-to-school and holiday gift giving.

 

 

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FDA May Revoke Approval of Avastin for Breast Cancer Marking the Start of ‘Death Panel’ Drug Rationing

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US regulators will delay consideration of the colon-cancer drug Avastin as a treatment for breast. cancer

America’s health watchdog is considering revoking its approval of the drug Avastin for use on women with advanced breast cancer, leading to accusations that it will mark the start of ‘death panel’ drug rationing.  A decision to rescind endorsement of the drug would reignite the highly charged debate over US health care reform and how much the state should spend on new and expensive treatments.

It’s Official: Men look at Women’s Breasts First

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David Letterman is famously guilty of looking down before looking up

Women often say that men tend to ogle at their breasts and their face is the last thing they notice, and now a scientific study has found evidence to prove them right.
Scientists have found that almost half – 47 per cent – of men first glance at a woman’s breasts. A third of the “first fixations” are on the waist and hips, while fewer than 20 per cent look at the woman’s face, reports the Daily Mail in UK.
In fact, breasts are not only the first thing men look at, they also glance at them for longer than any other body part, revealed experts. Many believe that the reason behind such male tendency could be evolutionary, as women with larger chests and slim waists – such as Jennifer Hawkins, Lara Bingle and Rachael Finch – have higher levels of the female hormone oestrogen, indicating greater fertility. But the researchers conceded that there could be a more prosaic explanation.
“Men may be looking more often at the breasts because they are simply aesthetically pleasing, regardless of the size,” the Daily Telegraph quoted them as saying.
Subjects tested by researchers from New Zealand’s University of Wellington were presented with six images of the same woman, digitally altered to increase or decrease the size of her bust, waist and hips. The scientists recorded which areas men looked at first, the number of times they looked, and how long their gaze lasted, using cameras and mirrors to measure tiny eye movements.
“Eighty per cent of first fixations were on the breasts and midriff. Men spent consistently more time looking at the breasts and also made significantly more fixations upon them than other regions,” the study concluded.
It also found that men began to gaze at the “components of the hourglass figure” within 0.2 seconds. The research also discovered that few glances were directed at the arms, lower legs and feet.

Women often say that men tend to ogle at their breasts and their face is the last thing they notice, and now a scientific study has found evidence to prove them right. Scientists have found that almost half – 47 per cent – of men first glance at a woman’s breasts. A third of the “first fixations” are on the waist and hips, while fewer than 20 per cent look at the woman’s face, reports the Daily Mail in UK. (Pics)

Continue reading… “It’s Official: Men look at Women’s Breasts First”

Coming Soon, One-Shot Radiotherapy for Breast Cancer

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Radiotherapy for breast cancer patients could soon be a single dose 30-minute affair, instead of the tedious present-day regimen lasting over six weeks.
In a major breakthrough, a team of British doctors headed by University College London’s Dr Jayant S Vaidya — an Indian from Goa — has succesfully created and tested a new technique that will blast the remnants of a tumour inside the breast in just one shot, lasting half an hour. The team used radiation on areas just around the tumour rather than the whole breast, as is done presently.
A 10-year trial of this Targeted Intraoperative Radiotherapy (TIR), conducted in nine countries involving over 2,200 women, confirmed that radiation targeting a specific area of the breast was as effective as whole-breast radiation in reducing breast cancer recurrence in women.
The results of this trial was published in the latest edition of the medical journal ‘The Lancet’.
So, while a patient is still under anaesthesia following the removal of the tumour, a series of gentle X-rays are administered to destroy any remaining tumour cells at the cancer site. The technique is highly convenient, requiring just one session of radiation, making it less time consuming and less costly than whole-breast treatment.
“TARGIT trial can change two fundamental principles in the treatment of breast cancer: whole breast radiotherapy can be replaced by a targeted one-time shot and a much smaller dose of radiation may be adequate,” Dr Vaidya told TOI from UK. Several hospitals in India, including Breach Candy in Mumbai and AIIMS in Delhi, have expressed interest in his work, he added.
“Breast cancer usually recurs around the area where the tumour was detected the first time. So it’s logical to give concentrated dose of radiation to the tissues at highest risk of cancer coming back rather than the whole breast,” he added.
Dr Vaidya said that since 2000, the team started delivering TIR to patients. A special machine called Intrabeam administered radiation from inside the breast to the exact site of the cancer, instead of the present-day external beam radiotherapy.
“Our decade-long TARGIT trial has now confirmed that old and new methods are as good as each other,” Dr Vaidya said.
The therapy, however, has a few limitations at present. It can be done on patients over the age of 45 and the tumour should not be bigger than 3cm. “Our trials till now tried this technique on women above age of 45. So we don’t know how effective it will be in stopping recurrence of cancer on younger women. Trials to find this are going to start soon,” he said.
Dr Vaidya launched the TARGIT trial on March 24, 2000. In this randomized trial, women aged 45 years or older with breast cancer undergoing breast-conserving surgery were enrolled from 28 centres in nine countries. Patients were randomly assigned in a 1:1 ratio to receive TIR or whole-breast external beam radiotherapy.
The study said, “At four years, there were six local recurrences in the intraoperative radiotherapy group and five in the external beam radiotherapy group. Recurrence in the conserved breast at four years was 1.2% in the targeted intraoperative radiotherapy and 0.95% in the external beam radiotherapy group. Radiotherapy toxicity was lower in the TIR group.”
Prof Michael Baum, professor emeritus of surgery at University College London who carried out the first procedure using intraoperative radiotherapy in 1998 said, “Many women specially in the developing world who live hundreds of miles from a radiotherapy unit will be spared six weeks of treatment going back and forth to the radiotherapy centre.”
* Targeted Intraoperative Radiotherapy (TIR) has a comparable recurrence rate of around 1% with presently used external beam radiation
* Radiotherapy toxicity were four times lower, with an incidence rate of 0.5% compared with 2% from EBR
* The new technique involves an intense blast of radiation to the tumour site extending to a radius of 2 cm lasting 30 minutes
* It takes place after the surgeon has taken out the tumour and before the wound is closed
* TIR completely avoided irradiation of the heart, lung and oesophagus causing no damage to these structures
* It is currently only available to women taking part in clinical trials

Radiotherapy for breast cancer patients could soon be a single dose 30-minute affair, instead of the tedious present-day regimen lasting over six weeks.

In a major breakthrough, a team of British doctors headed by University College London’s Dr Jayant S Vaidya — an Indian from Goa — has succesfully created and tested a new technique that will blast the remnants of a tumour inside the breast in just one shot, lasting half an hour. The team used radiation on areas just around the tumour rather than the whole breast, as is done presently.

Continue reading… “Coming Soon, One-Shot Radiotherapy for Breast Cancer”

Fatwa Encouraging Adult Breastfeeding

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Controversy over adult breastfeeding.
A controversy is brewing in Saudi Arabia over a new fatwa issued that advocates, er, adult breastfeeding. From AOL News:
Sheikh Al Obeikan, an adviser to the royal court and consultant to the Ministry of Justice, set off a firestorm of controversy recently when he said on TV that women who come into regular contact with men who aren’t related to them ought to give them their breast milk so they will be considered relatives…

Stem Cell Therapy To Grow Bigger Breasts

Stem Cell Therapy To Grow Bigger Breasts

“You won’t believe it, until you see it” 

A STEM cell therapy offering “natural” breast enlargement is to be made available to British women for the first time.

The treatment could boost cup size while reducing stomach fat. It involves extracting stem cells from spare fat on the stomach or thighs and growing them in a woman’s breasts. An increase of one cup size is likely, with the potential for larger gains as the technique improves.

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Mini Submarines To Explore Human Body Nearing Reality

Mini Submarines To Explore Human Body Nearing Reality 

 

Ever since the 1966 Hollywood movie, doctors have imagined a real-life Fantastic Voyage  a medical vehicle shrunk small enough to “submarine” in and fix faulty cells in the body. Thanks to new research by Tel Aviv University scientists, that reality may be only three years away.

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Ten Minute Blood Test To Identify Cancer Proteins

Ten Minute Blood Test To Identify Cancer Proteins 

 A microfluidic chip identifies 35 proteins in a drop of blood within 10 minutes.

Measuring proteins in the blood can help doctors determine patients’ cancer risk and monitor the health of the elderly and people with chronic diseases. But current methods for testing these proteins are too expensive and require too much blood to be performed regularly. A microfluidic chip in clinical trials does on a single chip in 10 minutes what normally takes multiple technicians hours to do–and with just a single drop of blood. Researchers hope to make bedside diagnostics based on blood proteins a reality by bringing down the cost of such tests by at least an order of magnitude.

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