BY XAVIER BOFILL DE ROS

The first draft of the human genome was published 20 years ago in 2001, took nearly three years and cost between US$500 million and $1 billion. The Human Genome Project has allowed scientists to read, almost end to end, the 3 billion pairs of DNA bases – or “letters” – that biologically define a human being.

That project has allowed a new generation of researchers like me, currently a postdoctoral fellow at the National Cancer Institute, to identify novel targets for cancer treatments, engineer mice with human immune systems and even build a webpage where anyone can navigate the entire human genome with the same ease with which you use Google Maps.

The first complete genome was generated from a handful of anonymous donors to try to produce a reference genome that represented more than just one single individual. But this fell far short of encompassing the wide diversity of human populations in the world. No two people are the same and no two genomes are the same, either. If researchers wanted to understand humanity in all its diversity, it would take sequencing thousands or millions of complete genomes. Now, a project like that is underway.

By DOUG NORRIE 

You’ve seen Planet of the Apes right? Did you like how that movie turned out in the end? I’ll give you the cliff notes. The apes won. Well, it appears scientists didn’t get the memo about what happens when we start supercharging primates or just start combining human-related things with monkeys. And sure, I know that monkeys and apes aren’t the same thing, but for our dystopian sci-fi purposes let’s just call it a wash. Because this latest news is pretty groundbreaking. According to a journal article published in The Cell, it turns out that scientists have successfully combined human and monkey embryos for the first time. Good luck world, I think we know how this ends. 

This study that landed monkey and human embryos all mixed up together started like all of these things usually do, with someone trying to solve a medical issue. Sure, fine enough. The problem, in this case, had to do with organ transplants and finding a way to better source said organs for procedures. In doing so, scientists began experimentation around cross-breeding these embryos, finding that those of the monkey allowed the process to speed up. Whether this ultimately becomes a good thing in their findings remains to be seen, but for the time being, they have at least proved it to be possible. 

The article was published on April 15th as part of a larger study in which human stem cells were injected into monkey embryos. The results were nearly immediate with researchers showing signs of growth within more than 100 monkeys. They are titling this process, an ominous one called a chimeric embryo, relating to the chimera of Greek Myth. You might know this bad boy as the combination of a bunch of different animals to form one scary super animal. This isn’t an interpretation, this is something actually quoted in the study. Though they stop short of referencing the exact fire-breathing monster the Greeks came up with that’s equal part lion, goat, and serpent.