Researchers discovered a small molecule that inhibits an enzyme that degrades insulin.
Harvard researchers may have finally identified a chemical compound that could be used to study and treat diabetes after decades of searching. They have discovered a whole different method for maintaining insulin in the blood: by blocking the enzyme that breaks it down.
Our breathprint could be used to detect signature metabolites associated with disease.
Our fingerprints are unique to us, but so may be our breath. Compounds in exhaled air produce a unique and stable molecular autograph or “breathprint” – one that could be used to monitor disease or track response to medication.
This is an artist’s concept of excess left-hand aspartic acid created in asteroids and delivered to Earth via meteorite impacts. The line at the bottom is a chromatogram showing that left-hand aspartic acid (tall peak in the center, with diagram of left-hand aspartic acid molecule on top) was four times more abundant in the meteorite sample than right-hand aspartic acid (smaller peak to the left, with right-handed aspartic acid molecule on top).
Researchers analyzing meteorite fragments that fell on a frozen lake in Canada have developed an explanation for the origin of life’s handedness — why living things only use molecules with specific orientations. The work also gave the strongest evidence to date that liquid water inside an asteroid leads to a strong preference of left-handed over right-handed forms of some common protein amino acids in meteorites. The result makes the search for extraterrestrial life more challenging…
Eating less turns on a molecule that helps the brain stay young.
Overeating can cause brain aging while eating less turns on a molecule that helps the brain stay young. Researchers at the Catholic University of Sacred Heart in Rome have discovered that a molecule, called CREB1, is triggered by “caloric restriction” (low caloric diet) in the brain of mice. They found that CREB1 activates many genes linked to longevity and to the proper functioning of the brain.