A “game-changing” antibiotic could be used as a “last line of defence” against superbugs to save millions of lives from otherwise drug-resistant infections after a breakthrough by UK scientists, a study suggests.
By Nina Lloyd
Researchers say they have developed new versions of the molecule teixobactin, which is thought to be capable of killing bacteria without damaging mammalian tissue.
Teixobactin was first hailed as a “game-changing” antibiotic in 2015, but the new project has developed “synthetic” classes of the drug, according to scientists.
These versions could destroy a wide range of microbes taken from human patients, a team including researchers from the University of Liverpool has found.
They also successfully eradicated methicillin-resistant Staphylococcus aureus – a so-called superbug known as MRSA, which is resistant to several widely used antibiotics – in a study on mice.
More than 1.2 million people died in 2019 from antibiotic-resistant bacterial infections, according to a study published in The Lancet in January.
Scientists said the tests suggested that in future, patients may be treated with just one dose of teixobactin per day for systemic life-threatening resistant bacterial infections.
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