World-first gene therapy reverses Alzheimer’s memory loss in mice

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Research into Alzheimer’s-related memory loss has uncovered an exciting new breakthrough in the form of a world-first gene therapy

Scientists in Australia have made an exciting breakthrough in Alzheimer’s research, demonstrating what they describe as the first gene-therapy-based approach for treating advanced forms of the disease. Through experiments in mice, the team was able to show how activating a key enzyme in the brain can prevent the kind of memory loss associated with advanced forms of Alzheimer’s, and even reverse it.

The research was carried out at Macquarie University, where dementia researchers and brothers Lars and Arne Ittner were investigating the role of a key enzyme in the brain called p38gamma. Through previous research, the brothers had shown that by activating this enzyme in mice with advanced dementia, they could modify a protein that prevents the development of Alzheimer’s symptoms.

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Study finds nasal spray effective treatment for Alzheimer’s and memory loss

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Nasal spray could improve memory in people with Alzheimer’s disease.

A new study published in the Journal of Alzheimer’s Disease found that an insulin nasal spray can improve cognitive function in those with Alzheimer’s disease and normal age-related memory problems. The study involved 60 adults who had normal age-related memory problems or mild to moderate Alzheimer’s (Claxton et al., 2015).

 

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Memory loss from Alzheimer’s disease reversed with lifestyle changes

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This is the first time researchers have been able to reverse the memory loss caused by the disease.

The first time ever, huge lifestyle interventions seems to have reversed memory loss caused by Alzheimer’s disease in some patients.. The findings stemmed from the joint efforts of a team from UCLA’s Mary S. Easton Center for Alzheimer’s Disease Research and the Buck Institute for Research on Aging.

 

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Novel treatment may reverse memory loss in Alzheimer’s patients

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Nine out of ten patients with memory problems showed improvements with this novel multi-systems approach.

A small exploratory study has found that memory loss in patients with Alzheimer’s disease may be reversed — and the improvement sustained — using a novel treatment approach.

 

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Overeating may increase risk of memory loss

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The more calories older people consumed, the more likely they were to have mild cognitive impairment.

Overeating may increase your risk of memory loss.  Older people who consumed more than 2,143 calories a day had more than double the risk of a type of memory loss called mild cognitive impairment compared to those who ate fewer than 1,500 calories a day, according to a study being released Sunday by the American Academy of Neurology on its website (aan.com).

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