Prof. Pierre-Alain Clavien and Prof. Philipp Dutkowski during the transplantation of the liver treated in the machine.
The Liver4Life research has developed a perfusion machine that makes it possible to implant a human organ into a patient after a storage period of three days outside a body. The machine mimics the human body as accurately as possible, in order to provide ideal conditions for human livers. A pump serves as a replacement heart, an oxygenator replaces the lungs and a dialysis unit performs the functions of the kidneys. In addition, numerous hormone and nutrient infusions perform the functions of the intestine and pancreas.
Like the diaphragm in the human body, the machine also moves the liver to the rhythm of human breathing. In January 2020, the multidisciplinary Zurich research team—involving the collaboration of University Hospital Zurich (USZ), ETH Zurich and the University of Zurich (UZH)—demonstrated for the first time that perfusion technology makes it possible to store a liver outside the body for several days.
Continue reading… “A world first: Human liver was treated in a machine and then successfully transplanted”
