Old human cells rejuvenated with stem cell technology, research finds

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Old human cells return to a more youthful and vigorous state after being induced to briefly express a panel of proteins involved in embryonic development, according to a new study by researchers at the Stanford University School of Medicine.

The researchers also found that elderly mice regained youthful strength after their existing muscle stem cells were subjected to the rejuvenating protein treatment and transplanted back into their bodies.

The proteins, known as Yamanaka factors, are commonly used to transform an adult cell into what are known as induced pluripotent stem cells, or iPS cells. Induced pluripotent stem cells can become nearly any type of cell in the body, regardless of the cell from which they originated. They’ve become important in regenerative medicine and drug discovery.

The study found that inducing old human cells in a lab dish to briefly express these proteins rewinds many of the molecular hallmarks of aging and renders the treated cells nearly indistinguishable from their younger counterparts.

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How caloric restriction prevents negative effects of aging in cells

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Summary:

A new study provides the most detailed report to date of the cellular effects of a calorie-restricted diet in rats. While the benefits of caloric restriction have long been known, the new results show how this restriction can protect against aging in cellular pathways.

If you want to reduce levels of inflammation throughout your body, delay the onset of age-related diseases, and live longer, eat less food. That’s the conclusion of a new study by scientists from the US and China that provides the most detailed report to date of the cellular effects of a calorie-restricted diet in rats. While the benefits of caloric restriction have long been known, the new results show how this restriction can protect against aging in cellular pathways, as detailed in Cell on February 27, 2020.

“We already knew that calorie restriction increases life span, but now we’ve shown all the changes that occur at a single-cell level to cause that,” says Juan Carlos Izpisua Belmonte, a senior author of the new paper, professor in Salk’s Gene Expression Laboratory and holder of the Roger Guillemin Chair. “This gives us targets that we may eventually be able to act on with drugs to treat aging in humans.”

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Study finds aging tends to shift gears as you turn 34, 60 and 78

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It’s possible to predict a person’s age from protein levels in their blood according to a Stanford study

 The blood-borne signs of aging – and indeed, perhaps the causes of aging – make three big shifts around the ages of 34, 60 and 78, a new Stanford-led study has discovered, potentially leading to new diagnostic tests and avenues of anti-aging research.

The study measured levels of nearly 3,000 individual proteins in the plasma of small blood samples from 4,263 people aged between 18 and 95, and found that 1,379 of these proteins varied significantly with a subject’s age. Indeed, with information about levels of just 373 of these proteins, the researchers found they could predict a subject’s age “with great accuracy,” and an even smaller subset of just nine proteins could do a “passable” job.

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The ‘blood boy’ clinic is coming to NYC so rich people can live forever

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The way Dr. Jesse Karmazin sees it, New York City needs some fresh blood.

It’s been over a year since we last heard from the physician behind Ambrosia LLC, the company hoping to reverse aging by pumping adults with the blood plasma of the young, but don’t think for a second that Karmazin’s been sitting still. Far from it.

Karmazin confirmed today over email that he plans to transform what was once a clinical trial running out of Monterey, California, into a full-fledged New York City-based clinic offering that most elusive of products: youth.

And you’d better believe it will cost you.

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Company uses patient’s own cells to put and end to baldness, aging skin and tendon degeneration

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Hollywood has made movies about it. Industries have made billions from it. And if the volume of scripture is any indication, the Almighty God must have placed great value on his creation of the head of human hair. After all, He gave Samson—the strongest man of whom the Bible tells—his immense strength through his hair and declared a woman’s hair “a glory unto” her in the 11th chapter of 1 Chorinthians.

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Only 3% of seniors wait until 70 to collect social security even thought it’d mean a 76% larger payment

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Social Security is a program that forms the financial foundation for a majority of our nation’s retired workers, and that’s not expected to change anytime soon. We’re really dependent on Social Security income, and that could be a problem

Data from the Social Security Administration (SSA) shows that 61% of all current retired workers receiving benefits count on Social Security to provide at least half of their monthly income.

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New treatments show promise in prolonging human life

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Drugs to slow aging already exist in the form of relatively cheap medicines that have been used for other purposes for years.

There is evidence that some widely used drugs can prolong lifespan for well people – and insiders have started taking them off-label. Millions of people are taking anti-aging drugs every day – they just don’t know it. Drugs to slow aging sound futuristic but they already exist in the form of relatively cheap medicines that have been used for other purposes for decades.

 

 

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North Korea Hails New ‘Anti-Ageing Super Drink’

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Microelements make up the Super Drink
North Korea has developed a “super drink” that, it says, can multiply brain cells and stop skin ageing. The secretive state’s official news agency, KCNA, says the drink contains 60 kinds of “microelements” extracted from more than 30 species of plants.

It attracted “much interest from Chinese, German and other businessmen” at a trade fair in Pyongyang last month, the agency reports. It was developed by a joint venture fruit juice company. KCNA says: “It, with effects of both preventive and curative treatment, helps improve mental and retentive faculties by multiplying brain cells.

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