Gene-hacking mosquitoes to be infertile backfired spectacularly

 

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Best-Laid Plans

On its surface, the plan was simple: gene-hack mosquitoes so their offspring immediately die, mix them with disease-spreading bugs in the wild, and watch the population drop off. Unfortunately, that didn’t quite pan out.

The genetically-altered mosquitoes did mix with the wild population, and for a brief period the number of mosquitoes in Jacobino, Brazil did plummet, according to research published in Nature Scientific Reports last week. But 18 months later the population bounced right back up, New Atlas reports — and even worse, the new genetic hybrids may be even more resilient to future attempts to quell their numbers.

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Building a better brain-in-a-dish, faster and cheaper

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UC San Diego researchers develop new protocol for creating human cortical organoids, mini-brains derived directly from primary cells that can be used to better explore and understand the real thing.

Writing in the current online issue of the journal Stem Cells and Development , researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

Continue reading… “Building a better brain-in-a-dish, faster and cheaper”