In an article published in the May 22, 2023 issue of Cell Systems, a team of diverse scientists, led by researchers from the University of California San Diego School of Medicine, has developed an innovative map that unveils the intricate system within the human body responsible for addressing and repairing DNA damage—a crucial factor in the onset and progression of various diseases.
DNA damage and replication errors resulting from stress and other factors play a significant role in the development of diseases such as cancer and heritable neurological disorders. To maintain genomic integrity and support overall health, cells have evolved a sophisticated network of cell-cycle checkpoints and DNA damage repair tools collectively known as the DNA damage response (DDR).
Continue reading… “Unraveling the Complexity of DNA Repair: A Comprehensive Map Reveals New Insights”