Cancer therapies have seen great development over the decades. Radiotherapies and chemotherapies have saved countless lives, but the latest arsenal, adoptive cell therapies (ACT), has stirred most excitement. In ACT, cells are processed to enhance their anti-cancer immune effects and injected into the patient. A new study by CiRA Professor Shin Kaneko and colleagues shows how iPS cell technology can produce some of the most potent anti-cancer immune cells for ACT yet.
T cells are the primary cells used in ACT, as they are the immune cells in the body most capable of killing cancer. However, current strategies using T cells have several, limiting the number of patients who can benefit from ACT. The Kaneko lab is exploring iPS cell technology as a solution.
“We have to process the T cells before injecting them into the patient. This processing affects the quality. If we first process the cells as iPS cells and then differentiate them into T cells, we can avoid many of these problems,” he said.
Continue reading… “Building Stronger Anti-Cancer Therapies With Stem Cells”
